Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex
The NuA4 histone acetyltransferase complex is important for gene regulation, DNA repair processes and cell cycle progression. Here the authors give molecular insights into the NuA4 complex by presenting the cryo-EM structures of the NuA4 TEEAA (Tra1, Eaf1, Eaf5, actin, and Arp4) and TEEAA-piccolo Nu...
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2018
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oai:doaj.org-article:c8ee69022e22421198b9b8fdc83d54392021-12-02T15:34:45ZArchitecture of the Saccharomyces cerevisiae NuA4/TIP60 complex10.1038/s41467-018-03504-52041-1723https://doaj.org/article/c8ee69022e22421198b9b8fdc83d54392018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03504-5https://doaj.org/toc/2041-1723The NuA4 histone acetyltransferase complex is important for gene regulation, DNA repair processes and cell cycle progression. Here the authors give molecular insights into the NuA4 complex by presenting the cryo-EM structures of the NuA4 TEEAA (Tra1, Eaf1, Eaf5, actin, and Arp4) and TEEAA-piccolo NuA4 assemblies.Xuejuan WangSalar AhmadZhihui ZhangJacques CôtéGang CaiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q Xuejuan Wang Salar Ahmad Zhihui Zhang Jacques Côté Gang Cai Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex |
description |
The NuA4 histone acetyltransferase complex is important for gene regulation, DNA repair processes and cell cycle progression. Here the authors give molecular insights into the NuA4 complex by presenting the cryo-EM structures of the NuA4 TEEAA (Tra1, Eaf1, Eaf5, actin, and Arp4) and TEEAA-piccolo NuA4 assemblies. |
format |
article |
author |
Xuejuan Wang Salar Ahmad Zhihui Zhang Jacques Côté Gang Cai |
author_facet |
Xuejuan Wang Salar Ahmad Zhihui Zhang Jacques Côté Gang Cai |
author_sort |
Xuejuan Wang |
title |
Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex |
title_short |
Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex |
title_full |
Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex |
title_fullStr |
Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex |
title_full_unstemmed |
Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex |
title_sort |
architecture of the saccharomyces cerevisiae nua4/tip60 complex |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/c8ee69022e22421198b9b8fdc83d5439 |
work_keys_str_mv |
AT xuejuanwang architectureofthesaccharomycescerevisiaenua4tip60complex AT salarahmad architectureofthesaccharomycescerevisiaenua4tip60complex AT zhihuizhang architectureofthesaccharomycescerevisiaenua4tip60complex AT jacquescote architectureofthesaccharomycescerevisiaenua4tip60complex AT gangcai architectureofthesaccharomycescerevisiaenua4tip60complex |
_version_ |
1718386744506712064 |