ZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS

Abstract. The aim of the present research was to study the expression of Fas-receptor and differentiation antigens CD3, CD4, CD8, CD16, CD20 on mononuclear cells of peripheral blood in the group of people with asimptomatic Zn-deficiency caused by geochemical conditions (the Zn level in the soil &...

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Autor principal:	L. M. Karzakova
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	zinc deficiency apoptosis immunodeficiency Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/c8f9156d53e544e9986f5c713a706b0b
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spelling	oai:doaj.org-article:c8f9156d53e544e9986f5c713a706b0b2021-11-18T08:03:41ZZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS1563-06252313-741X10.15789/1563-0625-2005-4-441-443https://doaj.org/article/c8f9156d53e544e9986f5c713a706b0b2014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/510https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. The aim of the present research was to study the expression of Fas-receptor and differentiation antigens CD3, CD4, CD8, CD16, CD20 on mononuclear cells of peripheral blood in the group of people with asimptomatic Zn-deficiency caused by geochemical conditions (the Zn level in the soil < 0,1 mg/kg and in human diet 9,1 mg /d at norm 15 mg/d). Simultaneously, we estimated lymphocyte proliferative activity characterizing the cell functional state contrary to apoptosis. We found the association of Zn - deficiency with insufficiency of the T-cell compartment of the immune system most likely caused by accelerated apoptosis of T-lymphocytes.L. M. KarzakovaSPb RAACIarticlezinc deficiencyapoptosisimmunodeficiencyImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 7, Iss 4, Pp 441-443 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	zinc deficiency apoptosis immunodeficiency Immunologic diseases. Allergy RC581-607
spellingShingle	zinc deficiency apoptosis immunodeficiency Immunologic diseases. Allergy RC581-607 L. M. Karzakova ZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS
description	Abstract. The aim of the present research was to study the expression of Fas-receptor and differentiation antigens CD3, CD4, CD8, CD16, CD20 on mononuclear cells of peripheral blood in the group of people with asimptomatic Zn-deficiency caused by geochemical conditions (the Zn level in the soil < 0,1 mg/kg and in human diet 9,1 mg /d at norm 15 mg/d). Simultaneously, we estimated lymphocyte proliferative activity characterizing the cell functional state contrary to apoptosis. We found the association of Zn - deficiency with insufficiency of the T-cell compartment of the immune system most likely caused by accelerated apoptosis of T-lymphocytes.
format	article
author	L. M. Karzakova
author_facet	L. M. Karzakova
author_sort	L. M. Karzakova
title	ZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS
title_short	ZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS
title_full	ZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS
title_fullStr	ZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS
title_full_unstemmed	ZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS
title_sort	zinc deficiency induces fas-mediated apoptosis
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/c8f9156d53e544e9986f5c713a706b0b
work_keys_str_mv	AT lmkarzakova zincdeficiencyinducesfasmediatedapoptosis
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ZINC DEFICIENCY INDUCES FAS-MEDIATED APOPTOSIS

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