The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning

Brain cytoplasmic (BC1) RNA is a non-coding RNA that has been implicated in translational regulation, seizure, and anxiety. Here, the authors show that in the cortex, BC1 RNA is required for sensory deprivation-induced structural plasticity of dendritic spines, as well as for correct sensory learnin...

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Autores principales: Victor Briz, Leonardo Restivo, Emanuela Pasciuto, Konrad Juczewski, Valentina Mercaldo, Adrian C. Lo, Pieter Baatsen, Natalia V. Gounko, Antonella Borreca, Tiziana Girardi, Rossella Luca, Julie Nys, Rogier B. Poorthuis, Huibert D. Mansvelder, Gilberto Fisone, Martine Ammassari-Teule, Lutgarde Arckens, Patrik Krieger, Rhiannon Meredith, Claudia Bagni
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c904b79eda0c41d194c02e95b2cd0dea
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spelling oai:doaj.org-article:c904b79eda0c41d194c02e95b2cd0dea2021-12-02T14:16:55ZThe non-coding RNA BC1 regulates experience-dependent structural plasticity and learning10.1038/s41467-017-00311-22041-1723https://doaj.org/article/c904b79eda0c41d194c02e95b2cd0dea2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00311-2https://doaj.org/toc/2041-1723Brain cytoplasmic (BC1) RNA is a non-coding RNA that has been implicated in translational regulation, seizure, and anxiety. Here, the authors show that in the cortex, BC1 RNA is required for sensory deprivation-induced structural plasticity of dendritic spines, as well as for correct sensory learning and social behaviors.Victor BrizLeonardo RestivoEmanuela PasciutoKonrad JuczewskiValentina MercaldoAdrian C. LoPieter BaatsenNatalia V. GounkoAntonella BorrecaTiziana GirardiRossella LucaJulie NysRogier B. PoorthuisHuibert D. MansvelderGilberto FisoneMartine Ammassari-TeuleLutgarde ArckensPatrik KriegerRhiannon MeredithClaudia BagniNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Victor Briz
Leonardo Restivo
Emanuela Pasciuto
Konrad Juczewski
Valentina Mercaldo
Adrian C. Lo
Pieter Baatsen
Natalia V. Gounko
Antonella Borreca
Tiziana Girardi
Rossella Luca
Julie Nys
Rogier B. Poorthuis
Huibert D. Mansvelder
Gilberto Fisone
Martine Ammassari-Teule
Lutgarde Arckens
Patrik Krieger
Rhiannon Meredith
Claudia Bagni
The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning
description Brain cytoplasmic (BC1) RNA is a non-coding RNA that has been implicated in translational regulation, seizure, and anxiety. Here, the authors show that in the cortex, BC1 RNA is required for sensory deprivation-induced structural plasticity of dendritic spines, as well as for correct sensory learning and social behaviors.
format article
author Victor Briz
Leonardo Restivo
Emanuela Pasciuto
Konrad Juczewski
Valentina Mercaldo
Adrian C. Lo
Pieter Baatsen
Natalia V. Gounko
Antonella Borreca
Tiziana Girardi
Rossella Luca
Julie Nys
Rogier B. Poorthuis
Huibert D. Mansvelder
Gilberto Fisone
Martine Ammassari-Teule
Lutgarde Arckens
Patrik Krieger
Rhiannon Meredith
Claudia Bagni
author_facet Victor Briz
Leonardo Restivo
Emanuela Pasciuto
Konrad Juczewski
Valentina Mercaldo
Adrian C. Lo
Pieter Baatsen
Natalia V. Gounko
Antonella Borreca
Tiziana Girardi
Rossella Luca
Julie Nys
Rogier B. Poorthuis
Huibert D. Mansvelder
Gilberto Fisone
Martine Ammassari-Teule
Lutgarde Arckens
Patrik Krieger
Rhiannon Meredith
Claudia Bagni
author_sort Victor Briz
title The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning
title_short The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning
title_full The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning
title_fullStr The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning
title_full_unstemmed The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning
title_sort non-coding rna bc1 regulates experience-dependent structural plasticity and learning
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/c904b79eda0c41d194c02e95b2cd0dea
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