The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning
Brain cytoplasmic (BC1) RNA is a non-coding RNA that has been implicated in translational regulation, seizure, and anxiety. Here, the authors show that in the cortex, BC1 RNA is required for sensory deprivation-induced structural plasticity of dendritic spines, as well as for correct sensory learnin...
Guardado en:
Autores principales: | , , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/c904b79eda0c41d194c02e95b2cd0dea |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:c904b79eda0c41d194c02e95b2cd0dea |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:c904b79eda0c41d194c02e95b2cd0dea2021-12-02T14:16:55ZThe non-coding RNA BC1 regulates experience-dependent structural plasticity and learning10.1038/s41467-017-00311-22041-1723https://doaj.org/article/c904b79eda0c41d194c02e95b2cd0dea2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00311-2https://doaj.org/toc/2041-1723Brain cytoplasmic (BC1) RNA is a non-coding RNA that has been implicated in translational regulation, seizure, and anxiety. Here, the authors show that in the cortex, BC1 RNA is required for sensory deprivation-induced structural plasticity of dendritic spines, as well as for correct sensory learning and social behaviors.Victor BrizLeonardo RestivoEmanuela PasciutoKonrad JuczewskiValentina MercaldoAdrian C. LoPieter BaatsenNatalia V. GounkoAntonella BorrecaTiziana GirardiRossella LucaJulie NysRogier B. PoorthuisHuibert D. MansvelderGilberto FisoneMartine Ammassari-TeuleLutgarde ArckensPatrik KriegerRhiannon MeredithClaudia BagniNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Victor Briz Leonardo Restivo Emanuela Pasciuto Konrad Juczewski Valentina Mercaldo Adrian C. Lo Pieter Baatsen Natalia V. Gounko Antonella Borreca Tiziana Girardi Rossella Luca Julie Nys Rogier B. Poorthuis Huibert D. Mansvelder Gilberto Fisone Martine Ammassari-Teule Lutgarde Arckens Patrik Krieger Rhiannon Meredith Claudia Bagni The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning |
description |
Brain cytoplasmic (BC1) RNA is a non-coding RNA that has been implicated in translational regulation, seizure, and anxiety. Here, the authors show that in the cortex, BC1 RNA is required for sensory deprivation-induced structural plasticity of dendritic spines, as well as for correct sensory learning and social behaviors. |
format |
article |
author |
Victor Briz Leonardo Restivo Emanuela Pasciuto Konrad Juczewski Valentina Mercaldo Adrian C. Lo Pieter Baatsen Natalia V. Gounko Antonella Borreca Tiziana Girardi Rossella Luca Julie Nys Rogier B. Poorthuis Huibert D. Mansvelder Gilberto Fisone Martine Ammassari-Teule Lutgarde Arckens Patrik Krieger Rhiannon Meredith Claudia Bagni |
author_facet |
Victor Briz Leonardo Restivo Emanuela Pasciuto Konrad Juczewski Valentina Mercaldo Adrian C. Lo Pieter Baatsen Natalia V. Gounko Antonella Borreca Tiziana Girardi Rossella Luca Julie Nys Rogier B. Poorthuis Huibert D. Mansvelder Gilberto Fisone Martine Ammassari-Teule Lutgarde Arckens Patrik Krieger Rhiannon Meredith Claudia Bagni |
author_sort |
Victor Briz |
title |
The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning |
title_short |
The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning |
title_full |
The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning |
title_fullStr |
The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning |
title_full_unstemmed |
The non-coding RNA BC1 regulates experience-dependent structural plasticity and learning |
title_sort |
non-coding rna bc1 regulates experience-dependent structural plasticity and learning |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/c904b79eda0c41d194c02e95b2cd0dea |
work_keys_str_mv |
AT victorbriz thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT leonardorestivo thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT emanuelapasciuto thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT konradjuczewski thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT valentinamercaldo thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT adrianclo thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT pieterbaatsen thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT nataliavgounko thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT antonellaborreca thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT tizianagirardi thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT rossellaluca thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT julienys thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT rogierbpoorthuis thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT huibertdmansvelder thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT gilbertofisone thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT martineammassariteule thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT lutgardearckens thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT patrikkrieger thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT rhiannonmeredith thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT claudiabagni thenoncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT victorbriz noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT leonardorestivo noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT emanuelapasciuto noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT konradjuczewski noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT valentinamercaldo noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT adrianclo noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT pieterbaatsen noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT nataliavgounko noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT antonellaborreca noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT tizianagirardi noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT rossellaluca noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT julienys noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT rogierbpoorthuis noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT huibertdmansvelder noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT gilbertofisone noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT martineammassariteule noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT lutgardearckens noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT patrikkrieger noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT rhiannonmeredith noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning AT claudiabagni noncodingrnabc1regulatesexperiencedependentstructuralplasticityandlearning |
_version_ |
1718391692405506048 |