Hepatic protein tyrosine phosphatase receptor gamma links obesity-induced inflammation to insulin resistance

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Hepatic protein tyrosine phosphatase receptor gamma links obesity-induced inflammation to insulin resistance

During obesity, chronic inflammation leads to insulin resistance and diabetes. Here, Brenachot et al. show that Protein Tyrosine Phosphatase Receptor Gamma is upregulated in obesity by inflammatory signals and correlates with insulin resistance in humans. Its deletion in mouse models of obesity and...

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Détails bibliographiques
Auteurs principaux:	Xavier Brenachot, Giorgio Ramadori, Rafael M. Ioris, Christelle Veyrat-Durebex, Jordi Altirriba, Ebru Aras, Sanda Ljubicic, Daisuke Kohno, Salvatore Fabbiano, Sophie Clement, Nicolas Goossens, Mirko Trajkovski, Sheila Harroch, Francesco Negro, Roberto Coppari
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2017
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/c9087c97e4584399b00b49105c3d6c1d
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

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