Assisting PNA transport through cystic fibrosis human airway epithelia with biodegradable hybrid lipid-polymer nanoparticles

Assisting PNA transport through cystic fibrosis human airway epithelia with biodegradable hybrid lipid-polymer nanoparticles

Abstract Cystic fibrosis (CF) is characterized by an airway obstruction caused by a thick mucus due to a malfunctioning Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein. The sticky mucus restricts drugs in reaching target cells limiting the efficiency of treatments. The development...

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Autores principales: Marika Comegna, Gemma Conte, Andrea Patrizia Falanga, Maria Marzano, Gustavo Cernera, Antonella Miriam Di Lullo, Felice Amato, Nicola Borbone, Stefano D’Errico, Francesca Ungaro, Ivana d’Angelo, Giorgia Oliviero, Giuseppe Castaldo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/c90d998c17c94a5e9958764703a866ce
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