Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery

Hypoxic brain damage associated with premature birth causes lasting neurological impairments. Here, the authors use environmental enrichment to rescue white matter dysmaturation following hypoxia, while identifying a critical window of intervention and oligodendrocyte-specific changes in gene expres...

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Autores principales: Thomas A. Forbes, Evan Z. Goldstein, Jeffrey L. Dupree, Beata Jablonska, Joseph Scafidi, Katrina L. Adams, Yuka Imamura, Kazue Hashimoto-Torii, Vittorio Gallo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c910fba7abca44ef8ee57cdd37894dc5
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spelling oai:doaj.org-article:c910fba7abca44ef8ee57cdd37894dc52021-12-02T14:42:15ZEnvironmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery10.1038/s41467-020-14762-72041-1723https://doaj.org/article/c910fba7abca44ef8ee57cdd37894dc52020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14762-7https://doaj.org/toc/2041-1723Hypoxic brain damage associated with premature birth causes lasting neurological impairments. Here, the authors use environmental enrichment to rescue white matter dysmaturation following hypoxia, while identifying a critical window of intervention and oligodendrocyte-specific changes in gene expression.Thomas A. ForbesEvan Z. GoldsteinJeffrey L. DupreeBeata JablonskaJoseph ScafidiKatrina L. AdamsYuka ImamuraKazue Hashimoto-ToriiVittorio GalloNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Thomas A. Forbes
Evan Z. Goldstein
Jeffrey L. Dupree
Beata Jablonska
Joseph Scafidi
Katrina L. Adams
Yuka Imamura
Kazue Hashimoto-Torii
Vittorio Gallo
Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery
description Hypoxic brain damage associated with premature birth causes lasting neurological impairments. Here, the authors use environmental enrichment to rescue white matter dysmaturation following hypoxia, while identifying a critical window of intervention and oligodendrocyte-specific changes in gene expression.
format article
author Thomas A. Forbes
Evan Z. Goldstein
Jeffrey L. Dupree
Beata Jablonska
Joseph Scafidi
Katrina L. Adams
Yuka Imamura
Kazue Hashimoto-Torii
Vittorio Gallo
author_facet Thomas A. Forbes
Evan Z. Goldstein
Jeffrey L. Dupree
Beata Jablonska
Joseph Scafidi
Katrina L. Adams
Yuka Imamura
Kazue Hashimoto-Torii
Vittorio Gallo
author_sort Thomas A. Forbes
title Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery
title_short Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery
title_full Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery
title_fullStr Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery
title_full_unstemmed Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery
title_sort environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/c910fba7abca44ef8ee57cdd37894dc5
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