Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery
Hypoxic brain damage associated with premature birth causes lasting neurological impairments. Here, the authors use environmental enrichment to rescue white matter dysmaturation following hypoxia, while identifying a critical window of intervention and oligodendrocyte-specific changes in gene expres...
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Nature Portfolio
2020
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oai:doaj.org-article:c910fba7abca44ef8ee57cdd37894dc52021-12-02T14:42:15ZEnvironmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery10.1038/s41467-020-14762-72041-1723https://doaj.org/article/c910fba7abca44ef8ee57cdd37894dc52020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14762-7https://doaj.org/toc/2041-1723Hypoxic brain damage associated with premature birth causes lasting neurological impairments. Here, the authors use environmental enrichment to rescue white matter dysmaturation following hypoxia, while identifying a critical window of intervention and oligodendrocyte-specific changes in gene expression.Thomas A. ForbesEvan Z. GoldsteinJeffrey L. DupreeBeata JablonskaJoseph ScafidiKatrina L. AdamsYuka ImamuraKazue Hashimoto-ToriiVittorio GalloNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020) |
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Science Q |
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Science Q Thomas A. Forbes Evan Z. Goldstein Jeffrey L. Dupree Beata Jablonska Joseph Scafidi Katrina L. Adams Yuka Imamura Kazue Hashimoto-Torii Vittorio Gallo Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery |
description |
Hypoxic brain damage associated with premature birth causes lasting neurological impairments. Here, the authors use environmental enrichment to rescue white matter dysmaturation following hypoxia, while identifying a critical window of intervention and oligodendrocyte-specific changes in gene expression. |
format |
article |
author |
Thomas A. Forbes Evan Z. Goldstein Jeffrey L. Dupree Beata Jablonska Joseph Scafidi Katrina L. Adams Yuka Imamura Kazue Hashimoto-Torii Vittorio Gallo |
author_facet |
Thomas A. Forbes Evan Z. Goldstein Jeffrey L. Dupree Beata Jablonska Joseph Scafidi Katrina L. Adams Yuka Imamura Kazue Hashimoto-Torii Vittorio Gallo |
author_sort |
Thomas A. Forbes |
title |
Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery |
title_short |
Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery |
title_full |
Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery |
title_fullStr |
Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery |
title_full_unstemmed |
Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery |
title_sort |
environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/c910fba7abca44ef8ee57cdd37894dc5 |
work_keys_str_mv |
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1718389778413518848 |