Trauma-focused treatments for depression. A systematic review and meta-analysis.

<h4>Background</h4>Trauma-focused treatments (TFTs) have demonstrated efficacy at decreasing depressive symptoms in individuals with PTSD. This systematic review and meta-analysis evaluated the effectiveness of TFTs for individuals with depression as their primary concern.<h4>Metho...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sarah K Dominguez, Suzy J M A Matthijssen, Christopher William Lee
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/c91e3859d03648448656f74c251f2dba
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c91e3859d03648448656f74c251f2dba
record_format	dspace
spelling	oai:doaj.org-article:c91e3859d03648448656f74c251f2dba2021-12-02T20:06:38ZTrauma-focused treatments for depression. A systematic review and meta-analysis.1932-620310.1371/journal.pone.0254778https://doaj.org/article/c91e3859d03648448656f74c251f2dba2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0254778https://doaj.org/toc/1932-6203<h4>Background</h4>Trauma-focused treatments (TFTs) have demonstrated efficacy at decreasing depressive symptoms in individuals with PTSD. This systematic review and meta-analysis evaluated the effectiveness of TFTs for individuals with depression as their primary concern.<h4>Methods</h4>A systematic search was conducted for RCTs published before October 2019 in Cochrane CENTRAL, Pubmed, EMBASE, PsycInfo, and additional sources. Trials examining the impact of TFTs on participants with depression were included. Trials focusing on individuals with PTSD or another mental health condition were excluded. The primary outcome was the effect size for depression diagnosis or depressive symptoms. Heterogeneity, study quality, and publication bias were also explored.<h4>Results</h4>Eleven RCTs were included (n = 567) with ten of these using EMDR as the TFT and one using imagery rescripting. Analysis suggested these TFTs were effective in reducing depressive symptoms post-treatment with a large effect size [d = 1.17 (95% CI: 0.58~ 1.75)]. Removal of an outlier saw the effect size remain large [d = 0.83 (95% CI: 0.48~ 1.17)], while the heterogeneity decreased (I2 = 66%). Analysis of the 10 studies that used EMDR also showed a large effect [d = 1.30 (95% CI: 0.67~1.91)]. EMDR was superior to non trauma-focused CBT [d = 0.66 (95% CI: 0.31~1.02)] and analysis of EMDR and imagery rescripting studies suggest superiority over inactive control conditions [d = 1.19 (95% CI: 0.53~ 1.86)]. Analysis of follow-up data also supported the use of EMDR with this population [d = 0.71 (95% CI: 1.04~0.38)]. No publication bias was identified.<h4>Conclusions</h4>Current evidence suggests that EMDR can be an effective treatment for depression. There were insufficient RCTs on other trauma-focused interventions to conclude whether TFTs in general were effective for treating depression. Larger studies with robust methodology using EMDR and other trauma-focused interventions are needed to build on these findings.Sarah K DominguezSuzy J M A MatthijssenChristopher William LeePublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 7, p e0254778 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Sarah K Dominguez Suzy J M A Matthijssen Christopher William Lee Trauma-focused treatments for depression. A systematic review and meta-analysis.
description	<h4>Background</h4>Trauma-focused treatments (TFTs) have demonstrated efficacy at decreasing depressive symptoms in individuals with PTSD. This systematic review and meta-analysis evaluated the effectiveness of TFTs for individuals with depression as their primary concern.<h4>Methods</h4>A systematic search was conducted for RCTs published before October 2019 in Cochrane CENTRAL, Pubmed, EMBASE, PsycInfo, and additional sources. Trials examining the impact of TFTs on participants with depression were included. Trials focusing on individuals with PTSD or another mental health condition were excluded. The primary outcome was the effect size for depression diagnosis or depressive symptoms. Heterogeneity, study quality, and publication bias were also explored.<h4>Results</h4>Eleven RCTs were included (n = 567) with ten of these using EMDR as the TFT and one using imagery rescripting. Analysis suggested these TFTs were effective in reducing depressive symptoms post-treatment with a large effect size [d = 1.17 (95% CI: 0.58~ 1.75)]. Removal of an outlier saw the effect size remain large [d = 0.83 (95% CI: 0.48~ 1.17)], while the heterogeneity decreased (I2 = 66%). Analysis of the 10 studies that used EMDR also showed a large effect [d = 1.30 (95% CI: 0.67~1.91)]. EMDR was superior to non trauma-focused CBT [d = 0.66 (95% CI: 0.31~1.02)] and analysis of EMDR and imagery rescripting studies suggest superiority over inactive control conditions [d = 1.19 (95% CI: 0.53~ 1.86)]. Analysis of follow-up data also supported the use of EMDR with this population [d = 0.71 (95% CI: 1.04~0.38)]. No publication bias was identified.<h4>Conclusions</h4>Current evidence suggests that EMDR can be an effective treatment for depression. There were insufficient RCTs on other trauma-focused interventions to conclude whether TFTs in general were effective for treating depression. Larger studies with robust methodology using EMDR and other trauma-focused interventions are needed to build on these findings.
format	article
author	Sarah K Dominguez Suzy J M A Matthijssen Christopher William Lee
author_facet	Sarah K Dominguez Suzy J M A Matthijssen Christopher William Lee
author_sort	Sarah K Dominguez
title	Trauma-focused treatments for depression. A systematic review and meta-analysis.
title_short	Trauma-focused treatments for depression. A systematic review and meta-analysis.
title_full	Trauma-focused treatments for depression. A systematic review and meta-analysis.
title_fullStr	Trauma-focused treatments for depression. A systematic review and meta-analysis.
title_full_unstemmed	Trauma-focused treatments for depression. A systematic review and meta-analysis.
title_sort	trauma-focused treatments for depression. a systematic review and meta-analysis.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/c91e3859d03648448656f74c251f2dba
work_keys_str_mv	AT sarahkdominguez traumafocusedtreatmentsfordepressionasystematicreviewandmetaanalysis AT suzyjmamatthijssen traumafocusedtreatmentsfordepressionasystematicreviewandmetaanalysis AT christopherwilliamlee traumafocusedtreatmentsfordepressionasystematicreviewandmetaanalysis
_version_	1718375387136786432

Trauma-focused treatments for depression. A systematic review and meta-analysis.

Ejemplares similares