An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model

Al-Hity et al present a platform to study the tumour-immune interaction using a co-culture between cancer spheroids and activated immune cells. They assess the effects of cortisol application to the culture model as proof-of-concept, which demonstrates the potential for this platform as a screening...

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Autores principales: Gheed Al-Hity, FengWei Yang, Eduard Campillo-Funollet, Andrew E. Greenstein, Hazel Hunt, Myrthe Mampay, Haya Intabli, Marta Falcinelli, Anotida Madzvamuse, Chandrasekhar Venkataraman, Melanie S. Flint
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c934dd548ce34df6a207a29ad10e6bef
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spelling oai:doaj.org-article:c934dd548ce34df6a207a29ad10e6bef2021-12-02T17:44:54ZAn integrated framework for quantifying immune-tumour interactions in a 3D co-culture model10.1038/s42003-021-02296-72399-3642https://doaj.org/article/c934dd548ce34df6a207a29ad10e6bef2021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02296-7https://doaj.org/toc/2399-3642Al-Hity et al present a platform to study the tumour-immune interaction using a co-culture between cancer spheroids and activated immune cells. They assess the effects of cortisol application to the culture model as proof-of-concept, which demonstrates the potential for this platform as a screening tool for immunotherapy design.Gheed Al-HityFengWei YangEduard Campillo-FunolletAndrew E. GreensteinHazel HuntMyrthe MampayHaya IntabliMarta FalcinelliAnotida MadzvamuseChandrasekhar VenkataramanMelanie S. FlintNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Gheed Al-Hity
FengWei Yang
Eduard Campillo-Funollet
Andrew E. Greenstein
Hazel Hunt
Myrthe Mampay
Haya Intabli
Marta Falcinelli
Anotida Madzvamuse
Chandrasekhar Venkataraman
Melanie S. Flint
An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model
description Al-Hity et al present a platform to study the tumour-immune interaction using a co-culture between cancer spheroids and activated immune cells. They assess the effects of cortisol application to the culture model as proof-of-concept, which demonstrates the potential for this platform as a screening tool for immunotherapy design.
format article
author Gheed Al-Hity
FengWei Yang
Eduard Campillo-Funollet
Andrew E. Greenstein
Hazel Hunt
Myrthe Mampay
Haya Intabli
Marta Falcinelli
Anotida Madzvamuse
Chandrasekhar Venkataraman
Melanie S. Flint
author_facet Gheed Al-Hity
FengWei Yang
Eduard Campillo-Funollet
Andrew E. Greenstein
Hazel Hunt
Myrthe Mampay
Haya Intabli
Marta Falcinelli
Anotida Madzvamuse
Chandrasekhar Venkataraman
Melanie S. Flint
author_sort Gheed Al-Hity
title An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model
title_short An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model
title_full An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model
title_fullStr An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model
title_full_unstemmed An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model
title_sort integrated framework for quantifying immune-tumour interactions in a 3d co-culture model
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/c934dd548ce34df6a207a29ad10e6bef
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