An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model
Al-Hity et al present a platform to study the tumour-immune interaction using a co-culture between cancer spheroids and activated immune cells. They assess the effects of cortisol application to the culture model as proof-of-concept, which demonstrates the potential for this platform as a screening...
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Nature Portfolio
2021
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oai:doaj.org-article:c934dd548ce34df6a207a29ad10e6bef2021-12-02T17:44:54ZAn integrated framework for quantifying immune-tumour interactions in a 3D co-culture model10.1038/s42003-021-02296-72399-3642https://doaj.org/article/c934dd548ce34df6a207a29ad10e6bef2021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02296-7https://doaj.org/toc/2399-3642Al-Hity et al present a platform to study the tumour-immune interaction using a co-culture between cancer spheroids and activated immune cells. They assess the effects of cortisol application to the culture model as proof-of-concept, which demonstrates the potential for this platform as a screening tool for immunotherapy design.Gheed Al-HityFengWei YangEduard Campillo-FunolletAndrew E. GreensteinHazel HuntMyrthe MampayHaya IntabliMarta FalcinelliAnotida MadzvamuseChandrasekhar VenkataramanMelanie S. FlintNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021) |
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DOAJ |
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Biology (General) QH301-705.5 |
spellingShingle |
Biology (General) QH301-705.5 Gheed Al-Hity FengWei Yang Eduard Campillo-Funollet Andrew E. Greenstein Hazel Hunt Myrthe Mampay Haya Intabli Marta Falcinelli Anotida Madzvamuse Chandrasekhar Venkataraman Melanie S. Flint An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model |
description |
Al-Hity et al present a platform to study the tumour-immune interaction using a co-culture between cancer spheroids and activated immune cells. They assess the effects of cortisol application to the culture model as proof-of-concept, which demonstrates the potential for this platform as a screening tool for immunotherapy design. |
format |
article |
author |
Gheed Al-Hity FengWei Yang Eduard Campillo-Funollet Andrew E. Greenstein Hazel Hunt Myrthe Mampay Haya Intabli Marta Falcinelli Anotida Madzvamuse Chandrasekhar Venkataraman Melanie S. Flint |
author_facet |
Gheed Al-Hity FengWei Yang Eduard Campillo-Funollet Andrew E. Greenstein Hazel Hunt Myrthe Mampay Haya Intabli Marta Falcinelli Anotida Madzvamuse Chandrasekhar Venkataraman Melanie S. Flint |
author_sort |
Gheed Al-Hity |
title |
An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model |
title_short |
An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model |
title_full |
An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model |
title_fullStr |
An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model |
title_full_unstemmed |
An integrated framework for quantifying immune-tumour interactions in a 3D co-culture model |
title_sort |
integrated framework for quantifying immune-tumour interactions in a 3d co-culture model |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/c934dd548ce34df6a207a29ad10e6bef |
work_keys_str_mv |
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