The Application Status of Nanoscale Cellulose-Based Hydrogels in Tissue Engineering and Regenerative Biomedicine

As a renewable, biodegradable, and non-toxic material with moderate mechanical and thermal properties, nanocellulose-based hydrogels are receiving immense consideration for various biomedical applications. With the unique properties of excellent skeletal structure (hydrophilic functional groups) and...

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Autores principales:	Chenyang Wang, Jin Bai, Pei Tian, Rui Xie, Zifan Duan, Qinqin Lv, Yuqiang Tao
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	nanoscale cellulose hydrogel biomedicine non-toxic material Biotechnology TP248.13-248.65
Acceso en línea:	https://doaj.org/article/c937570d08cf4d91a7c0cddb8b3e6bba
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spelling	oai:doaj.org-article:c937570d08cf4d91a7c0cddb8b3e6bba2021-11-18T09:31:23ZThe Application Status of Nanoscale Cellulose-Based Hydrogels in Tissue Engineering and Regenerative Biomedicine2296-418510.3389/fbioe.2021.732513https://doaj.org/article/c937570d08cf4d91a7c0cddb8b3e6bba2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fbioe.2021.732513/fullhttps://doaj.org/toc/2296-4185As a renewable, biodegradable, and non-toxic material with moderate mechanical and thermal properties, nanocellulose-based hydrogels are receiving immense consideration for various biomedical applications. With the unique properties of excellent skeletal structure (hydrophilic functional groups) and micro-nano size (small size effect), nanocellulose can maintain the three-dimensional structure of the hydrogel to a large extent, providing mechanical strength while ensuring the moisture content. Owing to its unique features, nanocellulose-based hydrogels have made excellent progress in research and development on tissue engineering, drug carriers, wound dressings, development of synthetic organs, 3D printing, and biosensing. This review provides an overview of the synthesis of different types of nanocellulose, including cellulose nanocrystals, cellulose nanofibers, and bacterial nanocellulose, and describes their unique features. It further provides an updated knowledge of the development of nanocellulose-based functional biomaterials for various biomedical applications. Finally, it discusses the future perspective of nanocellulose-based research for its advanced biomedical applications.Chenyang WangJin BaiPei TianRui XieZifan DuanQinqin LvYuqiang TaoFrontiers Media S.A.articlenanoscalecellulosehydrogelbiomedicinenon-toxic materialBiotechnologyTP248.13-248.65ENFrontiers in Bioengineering and Biotechnology, Vol 9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	nanoscale cellulose hydrogel biomedicine non-toxic material Biotechnology TP248.13-248.65
spellingShingle	nanoscale cellulose hydrogel biomedicine non-toxic material Biotechnology TP248.13-248.65 Chenyang Wang Jin Bai Pei Tian Rui Xie Zifan Duan Qinqin Lv Yuqiang Tao The Application Status of Nanoscale Cellulose-Based Hydrogels in Tissue Engineering and Regenerative Biomedicine
description	As a renewable, biodegradable, and non-toxic material with moderate mechanical and thermal properties, nanocellulose-based hydrogels are receiving immense consideration for various biomedical applications. With the unique properties of excellent skeletal structure (hydrophilic functional groups) and micro-nano size (small size effect), nanocellulose can maintain the three-dimensional structure of the hydrogel to a large extent, providing mechanical strength while ensuring the moisture content. Owing to its unique features, nanocellulose-based hydrogels have made excellent progress in research and development on tissue engineering, drug carriers, wound dressings, development of synthetic organs, 3D printing, and biosensing. This review provides an overview of the synthesis of different types of nanocellulose, including cellulose nanocrystals, cellulose nanofibers, and bacterial nanocellulose, and describes their unique features. It further provides an updated knowledge of the development of nanocellulose-based functional biomaterials for various biomedical applications. Finally, it discusses the future perspective of nanocellulose-based research for its advanced biomedical applications.
format	article
author	Chenyang Wang Jin Bai Pei Tian Rui Xie Zifan Duan Qinqin Lv Yuqiang Tao
author_facet	Chenyang Wang Jin Bai Pei Tian Rui Xie Zifan Duan Qinqin Lv Yuqiang Tao
author_sort	Chenyang Wang
title	The Application Status of Nanoscale Cellulose-Based Hydrogels in Tissue Engineering and Regenerative Biomedicine
title_short	The Application Status of Nanoscale Cellulose-Based Hydrogels in Tissue Engineering and Regenerative Biomedicine
title_full	The Application Status of Nanoscale Cellulose-Based Hydrogels in Tissue Engineering and Regenerative Biomedicine
title_fullStr	The Application Status of Nanoscale Cellulose-Based Hydrogels in Tissue Engineering and Regenerative Biomedicine
title_full_unstemmed	The Application Status of Nanoscale Cellulose-Based Hydrogels in Tissue Engineering and Regenerative Biomedicine
title_sort	application status of nanoscale cellulose-based hydrogels in tissue engineering and regenerative biomedicine
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/c937570d08cf4d91a7c0cddb8b3e6bba
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The Application Status of Nanoscale Cellulose-Based Hydrogels in Tissue Engineering and Regenerative Biomedicine

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