Amniotic membrane extract and eye drops: a review of literature and clinical application

Michael S Murri,1 Majid Moshirfar,1,2 Orry C Birdsong,2 Yasmyne C Ronquillo,2 Yanning Ding,2 Phillip C Hoopes2 1John A Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, UT, USA; 2HDR Research Center, Hoopes Vision, Draper, UT,...

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Autores principales:	Murri MS, Moshirfar M, Birdsong OC, Ronquillo YC, Ding YN, Hoopes PC
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	Amniotic membrane Amniotic membrane extract Amniotic membrane extract eye drop AME AMEED AMT umbilical cord amnion Regenesol Genesis Regener-eyes corneal wound healing amniotic membrane transplant Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/c93c9b0b3dc54b1cacfc175f67d63d69
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spelling	oai:doaj.org-article:c93c9b0b3dc54b1cacfc175f67d63d692021-12-02T09:34:10ZAmniotic membrane extract and eye drops: a review of literature and clinical application1177-5483https://doaj.org/article/c93c9b0b3dc54b1cacfc175f67d63d692018-06-01T00:00:00Zhttps://www.dovepress.com/amniotic-membrane-extract-and-eye-drops-a-review-of-literature-and-cli-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Michael S Murri,1 Majid Moshirfar,1,2 Orry C Birdsong,2 Yasmyne C Ronquillo,2 Yanning Ding,2 Phillip C Hoopes2 1John A Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, UT, USA; 2HDR Research Center, Hoopes Vision, Draper, UT, USA Abstract: The amniotic membrane (AM) has a long history of use in the treatment of various diseases of the ocular surface. It contains pluripotent cells, highly organized collagen, anti-fibrotic and anti-inflammatory cytokines, immune-modulators, growth factors, and matrix proteins. It is used to promote corneal healing in severely damaged eyes. Recently, AM extract and AM extract eye drops have been successfully used in clinical applications, including dry eye and chemical burns. We provide an overview on the recent progress in the preparation, mechanisms of action, and use of AM extract/AM extract eye drops for corneal and external eye diseases. Keywords: amniotic membrane, amniotic membrane extract, amniotic membrane extract eye drops, AME, AMEED, AMT, umbilical cord, amnion, Regenesol, Genesis, Regener-Eyes, corneal wound healing, amniotic membrane transplantMurri MSMoshirfar MBirdsong OCRonquillo YCDing YNHoopes PCDove Medical PressarticleAmniotic membraneAmniotic membrane extractAmniotic membrane extract eye dropAMEAMEEDAMTumbilical cordamnionRegenesolGenesisRegener-eyescorneal wound healingamniotic membrane transplantOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 1105-1112 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Amniotic membrane Amniotic membrane extract Amniotic membrane extract eye drop AME AMEED AMT umbilical cord amnion Regenesol Genesis Regener-eyes corneal wound healing amniotic membrane transplant Ophthalmology RE1-994
spellingShingle	Amniotic membrane Amniotic membrane extract Amniotic membrane extract eye drop AME AMEED AMT umbilical cord amnion Regenesol Genesis Regener-eyes corneal wound healing amniotic membrane transplant Ophthalmology RE1-994 Murri MS Moshirfar M Birdsong OC Ronquillo YC Ding YN Hoopes PC Amniotic membrane extract and eye drops: a review of literature and clinical application
description	Michael S Murri,1 Majid Moshirfar,1,2 Orry C Birdsong,2 Yasmyne C Ronquillo,2 Yanning Ding,2 Phillip C Hoopes2 1John A Moran Eye Center, Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City, UT, USA; 2HDR Research Center, Hoopes Vision, Draper, UT, USA Abstract: The amniotic membrane (AM) has a long history of use in the treatment of various diseases of the ocular surface. It contains pluripotent cells, highly organized collagen, anti-fibrotic and anti-inflammatory cytokines, immune-modulators, growth factors, and matrix proteins. It is used to promote corneal healing in severely damaged eyes. Recently, AM extract and AM extract eye drops have been successfully used in clinical applications, including dry eye and chemical burns. We provide an overview on the recent progress in the preparation, mechanisms of action, and use of AM extract/AM extract eye drops for corneal and external eye diseases. Keywords: amniotic membrane, amniotic membrane extract, amniotic membrane extract eye drops, AME, AMEED, AMT, umbilical cord, amnion, Regenesol, Genesis, Regener-Eyes, corneal wound healing, amniotic membrane transplant
format	article
author	Murri MS Moshirfar M Birdsong OC Ronquillo YC Ding YN Hoopes PC
author_facet	Murri MS Moshirfar M Birdsong OC Ronquillo YC Ding YN Hoopes PC
author_sort	Murri MS
title	Amniotic membrane extract and eye drops: a review of literature and clinical application
title_short	Amniotic membrane extract and eye drops: a review of literature and clinical application
title_full	Amniotic membrane extract and eye drops: a review of literature and clinical application
title_fullStr	Amniotic membrane extract and eye drops: a review of literature and clinical application
title_full_unstemmed	Amniotic membrane extract and eye drops: a review of literature and clinical application
title_sort	amniotic membrane extract and eye drops: a review of literature and clinical application
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/c93c9b0b3dc54b1cacfc175f67d63d69
work_keys_str_mv	AT murrims amnioticmembraneextractandeyedropsareviewofliteratureandclinicalapplication AT moshirfarm amnioticmembraneextractandeyedropsareviewofliteratureandclinicalapplication AT birdsongoc amnioticmembraneextractandeyedropsareviewofliteratureandclinicalapplication AT ronquilloyc amnioticmembraneextractandeyedropsareviewofliteratureandclinicalapplication AT dingyn amnioticmembraneextractandeyedropsareviewofliteratureandclinicalapplication AT hoopespc amnioticmembraneextractandeyedropsareviewofliteratureandclinicalapplication
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Amniotic membrane extract and eye drops: a review of literature and clinical application

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