Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus

Noni (Morinda citrifolia) Increase Immune Response in Mice (Mus musculus) Infected Staphylococcus aureus. Infection disease caused by bacteria is one of the illness in several developing countries including in Indonesia, with high mortality rate. Infection of  S. aureus as the cause of problem resis...

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Autor principal: Mufidah Zumrotul
Formato: article
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Publicado: Universitas Nahdlatul Ulama Surabaya 2015
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Acceso en línea:https://doaj.org/article/c93cd7137d444d59b020bc0505321c58
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spelling oai:doaj.org-article:c93cd7137d444d59b020bc0505321c582021-12-02T07:56:55ZBuah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus1978-67432477-394810.33086/jhs.v6i2.34https://doaj.org/article/c93cd7137d444d59b020bc0505321c582015-11-01T00:00:00Zhttp://journal2.unusa.ac.id/index.php/JHS/article/view/34https://doaj.org/toc/1978-6743https://doaj.org/toc/2477-3948Noni (Morinda citrifolia) Increase Immune Response in Mice (Mus musculus) Infected Staphylococcus aureus. Infection disease caused by bacteria is one of the illness in several developing countries including in Indonesia, with high mortality rate. Infection of  S. aureus as the cause of problem resistance for antibiotic or multi drug resistance are giving the therapy of drug itself with change to medical herbal. The aim of this study is known the role of M.citrifoliaextract to increase immune response of mice with infectioned of S. aureus. Mice were divided into two groups there are Non Infection and infection. Non Infection is without S. aureus and than infection has S. aureus. The each groups are including control, dose 1 (25 mg/kg BW), dose 2 (100 mg/kg BW), and dose 3 (300 mg/kg BW). Relative number of lymphocyte T cell (CD4+) subsets was measured  using the BD FACSCaliburTM Flowcytometer. Data were analyzed using Analysis of Varians (p<0,05) and using SPSS 16 for windows. The result showed that administration of  M. citrifolia crude extract in non infection groups was significantly increase the relative amounts T cell subsets (CD4+). Noni fruit extract can used as prevention therapy on infection disease of S. aureus bacteria because it contains active compounds that are anti-inflammationMengkuduMufidah ZumrotulUniversitas Nahdlatul Ulama SurabayaarticleMengkuduStaphylococcusaureuslimfositCD4 TNursingRT1-120Medicine (General)R5-920ENIDJurnal Ilmiah Kesehatan, Vol 6, Iss 2 (2015)
institution DOAJ
collection DOAJ
language EN
ID
topic Mengkudu
Staphylococcus
aureus
limfosit
CD4
T
Nursing
RT1-120
Medicine (General)
R5-920
spellingShingle Mengkudu
Staphylococcus
aureus
limfosit
CD4
T
Nursing
RT1-120
Medicine (General)
R5-920
Mufidah Zumrotul
Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus
description Noni (Morinda citrifolia) Increase Immune Response in Mice (Mus musculus) Infected Staphylococcus aureus. Infection disease caused by bacteria is one of the illness in several developing countries including in Indonesia, with high mortality rate. Infection of  S. aureus as the cause of problem resistance for antibiotic or multi drug resistance are giving the therapy of drug itself with change to medical herbal. The aim of this study is known the role of M.citrifoliaextract to increase immune response of mice with infectioned of S. aureus. Mice were divided into two groups there are Non Infection and infection. Non Infection is without S. aureus and than infection has S. aureus. The each groups are including control, dose 1 (25 mg/kg BW), dose 2 (100 mg/kg BW), and dose 3 (300 mg/kg BW). Relative number of lymphocyte T cell (CD4+) subsets was measured  using the BD FACSCaliburTM Flowcytometer. Data were analyzed using Analysis of Varians (p<0,05) and using SPSS 16 for windows. The result showed that administration of  M. citrifolia crude extract in non infection groups was significantly increase the relative amounts T cell subsets (CD4+). Noni fruit extract can used as prevention therapy on infection disease of S. aureus bacteria because it contains active compounds that are anti-inflammationMengkudu
format article
author Mufidah Zumrotul
author_facet Mufidah Zumrotul
author_sort Mufidah Zumrotul
title Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus
title_short Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus
title_full Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus
title_fullStr Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus
title_full_unstemmed Buah Mengkudu (Morinda citrifolia) Meningkatkan Respon Imun Mencit (Mus musculus) Terhadap Infeksi Bakteri Staphylococcus aureus
title_sort buah mengkudu (morinda citrifolia) meningkatkan respon imun mencit (mus musculus) terhadap infeksi bakteri staphylococcus aureus
publisher Universitas Nahdlatul Ulama Surabaya
publishDate 2015
url https://doaj.org/article/c93cd7137d444d59b020bc0505321c58
work_keys_str_mv AT mufidahzumrotul buahmengkudumorindacitrifoliameningkatkanresponimunmencitmusmusculusterhadapinfeksibakteristaphylococcusaureus
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