Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level

Fine tuning the immune response in line with the degree of threat is central to recognition of a pathogen versus commensal bacteria. Here the authors implicate a digital all-or-nothing cell response in control of the tissue level immune response.

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Autores principales:	Helen R. Clark, Connor McKenney, Nathan M. Livingston, Ariel Gershman, Seema Sajjan, Isaac S. Chan, Andrew J. Ewald, Winston Timp, Bin Wu, Abhyudai Singh, Sergi Regot
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c941a781c5064d999cddc94eed6d7777
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spelling	oai:doaj.org-article:c941a781c5064d999cddc94eed6d77772021-12-02T16:36:00ZEpigenetically regulated digital signaling defines epithelial innate immunity at the tissue level10.1038/s41467-021-22070-x2041-1723https://doaj.org/article/c941a781c5064d999cddc94eed6d77772021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22070-xhttps://doaj.org/toc/2041-1723Fine tuning the immune response in line with the degree of threat is central to recognition of a pathogen versus commensal bacteria. Here the authors implicate a digital all-or-nothing cell response in control of the tissue level immune response.Helen R. ClarkConnor McKenneyNathan M. LivingstonAriel GershmanSeema SajjanIsaac S. ChanAndrew J. EwaldWinston TimpBin WuAbhyudai SinghSergi RegotNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Helen R. Clark Connor McKenney Nathan M. Livingston Ariel Gershman Seema Sajjan Isaac S. Chan Andrew J. Ewald Winston Timp Bin Wu Abhyudai Singh Sergi Regot Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level
description	Fine tuning the immune response in line with the degree of threat is central to recognition of a pathogen versus commensal bacteria. Here the authors implicate a digital all-or-nothing cell response in control of the tissue level immune response.
format	article
author	Helen R. Clark Connor McKenney Nathan M. Livingston Ariel Gershman Seema Sajjan Isaac S. Chan Andrew J. Ewald Winston Timp Bin Wu Abhyudai Singh Sergi Regot
author_facet	Helen R. Clark Connor McKenney Nathan M. Livingston Ariel Gershman Seema Sajjan Isaac S. Chan Andrew J. Ewald Winston Timp Bin Wu Abhyudai Singh Sergi Regot
author_sort	Helen R. Clark
title	Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level
title_short	Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level
title_full	Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level
title_fullStr	Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level
title_full_unstemmed	Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level
title_sort	epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c941a781c5064d999cddc94eed6d7777
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Epigenetically regulated digital signaling defines epithelial innate immunity at the tissue level

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