Sinonasal quality of life in patients after an endoscopic endonasal surgery of a sellar tumour

Abstract Endoscopic endonasal approach uses the nasal cavity and paranasal sinuses to access the cranial base and may be a source of post-surgical morbidity in many patients with a sellar tumour. The objective of the presented study was to evaluate sinonasal quality of life and assess the effect of...

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Autores principales:	Vlastimil Novák, L. Hrabálek, J. Hoza, C.Hučko, D. Pohlodek, J. Macura
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/c95df62ec8e6432593511298b03d2058
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spelling	oai:doaj.org-article:c95df62ec8e6432593511298b03d20582021-12-05T12:13:47ZSinonasal quality of life in patients after an endoscopic endonasal surgery of a sellar tumour10.1038/s41598-021-02747-52045-2322https://doaj.org/article/c95df62ec8e6432593511298b03d20582021-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02747-5https://doaj.org/toc/2045-2322Abstract Endoscopic endonasal approach uses the nasal cavity and paranasal sinuses to access the cranial base and may be a source of post-surgical morbidity in many patients with a sellar tumour. The objective of the presented study was to evaluate sinonasal quality of life and assess the effect of chosen reconstruction of the cranial base on the final condition. 65 patients, 33 male and 32 female who underwent an endoscopic endonasal surgery due to sellar expansion, were included into this prospective study. Sinonasal quality of life was evaluated using the Sinonasal Outcome Test-22 (SNOT-22) questionnaire before the surgery and six months after the surgery. Sinonasal quality of life was evaluated for the total cohort of patients and for patients after reconstruction (fascia lata, muscle) and without reconstruction. The minimum follow-up period was one year. There was no significant difference between the score (SNOT-22) before the surgery (average 14.4 points) and after the surgery (average 17.5 points), p = 0.067 in the whole cohort. Statistically significant differences were found in the following items—the need to blow nose, nasal congestion, loss of smell and taste, and thick discharge from the nose. The comparison of subgroups with and without the reconstruction yielded statistically significant differences in favour of patients with reconstruction in the following items—lack of high-quality sleep and feeling exhaustion. The endoscopic endonasal approach in patients with a sellar tumour is a gentle method with minimal effects on sinonasal quality of life over a period longer than six months. The most common complaints are the need to blow nose, nasal congestion, loss of smell and taste, and thick discharge from the nose. Cranial base reconstruction using the muscle and fascia lata seems to be a potential factor positively influencing sinonasal quality of life.Vlastimil NovákL. HrabálekJ. HozaC.HučkoD. PohlodekJ. MacuraNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Vlastimil Novák L. Hrabálek J. Hoza C.Hučko D. Pohlodek J. Macura Sinonasal quality of life in patients after an endoscopic endonasal surgery of a sellar tumour
description	Abstract Endoscopic endonasal approach uses the nasal cavity and paranasal sinuses to access the cranial base and may be a source of post-surgical morbidity in many patients with a sellar tumour. The objective of the presented study was to evaluate sinonasal quality of life and assess the effect of chosen reconstruction of the cranial base on the final condition. 65 patients, 33 male and 32 female who underwent an endoscopic endonasal surgery due to sellar expansion, were included into this prospective study. Sinonasal quality of life was evaluated using the Sinonasal Outcome Test-22 (SNOT-22) questionnaire before the surgery and six months after the surgery. Sinonasal quality of life was evaluated for the total cohort of patients and for patients after reconstruction (fascia lata, muscle) and without reconstruction. The minimum follow-up period was one year. There was no significant difference between the score (SNOT-22) before the surgery (average 14.4 points) and after the surgery (average 17.5 points), p = 0.067 in the whole cohort. Statistically significant differences were found in the following items—the need to blow nose, nasal congestion, loss of smell and taste, and thick discharge from the nose. The comparison of subgroups with and without the reconstruction yielded statistically significant differences in favour of patients with reconstruction in the following items—lack of high-quality sleep and feeling exhaustion. The endoscopic endonasal approach in patients with a sellar tumour is a gentle method with minimal effects on sinonasal quality of life over a period longer than six months. The most common complaints are the need to blow nose, nasal congestion, loss of smell and taste, and thick discharge from the nose. Cranial base reconstruction using the muscle and fascia lata seems to be a potential factor positively influencing sinonasal quality of life.
format	article
author	Vlastimil Novák L. Hrabálek J. Hoza C.Hučko D. Pohlodek J. Macura
author_facet	Vlastimil Novák L. Hrabálek J. Hoza C.Hučko D. Pohlodek J. Macura
author_sort	Vlastimil Novák
title	Sinonasal quality of life in patients after an endoscopic endonasal surgery of a sellar tumour
title_short	Sinonasal quality of life in patients after an endoscopic endonasal surgery of a sellar tumour
title_full	Sinonasal quality of life in patients after an endoscopic endonasal surgery of a sellar tumour
title_fullStr	Sinonasal quality of life in patients after an endoscopic endonasal surgery of a sellar tumour
title_full_unstemmed	Sinonasal quality of life in patients after an endoscopic endonasal surgery of a sellar tumour
title_sort	sinonasal quality of life in patients after an endoscopic endonasal surgery of a sellar tumour
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c95df62ec8e6432593511298b03d2058
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Sinonasal quality of life in patients after an endoscopic endonasal surgery of a sellar tumour

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