Inactivation of <italic toggle="yes">thyA</italic> in <named-content content-type="genus-species">Staphylococcus aureus</named-content> Attenuates Virulence and Has a Strong Impact on Metabolism and Virulence Gene Expression
ABSTRACT Staphylococcus aureus thymidine-dependent small-colony variants (TD-SCVs) are frequently isolated from patients with chronic S. aureus infections after long-term treatment with trimethoprim-sulfamethoxazole (TMP-SMX). While it has been shown that TD-SCVs were associated with mutations in th...
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Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2014
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Acceso en línea: | https://doaj.org/article/c969432815d641ee9c487fbaa84ee179 |
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