Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese
This genome-wide association study on persistent hepatitis B virus (HBV) infection among Chinese confirms previously associated genetic loci while discovering a novel protective locus at 8p21.3. The study also demonstrates the nearby gene INST10 suppresses HBV replication in vitro.
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Nature Portfolio
2016
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oai:doaj.org-article:c96b2ad71ac34492bddea1028cf805432021-12-02T14:40:11ZGenome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese10.1038/ncomms116642041-1723https://doaj.org/article/c96b2ad71ac34492bddea1028cf805432016-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms11664https://doaj.org/toc/2041-1723This genome-wide association study on persistent hepatitis B virus (HBV) infection among Chinese confirms previously associated genetic loci while discovering a novel protective locus at 8p21.3. The study also demonstrates the nearby gene INST10 suppresses HBV replication in vitro.Yuanfeng LiLanlan SiYun ZhaiYanling HuZhibin HuJin-Xin BeiBobo XieQian RenPengbo CaoFei YangQingfeng SongZhiyu BaoHaitao ZhangYuqing HanZhifu WangXi ChenXia XiaHongbo YanRui WangYing ZhangChengming GaoJinfeng MengXinyi TuXinqiang LiangYing CuiYing LiuXiaopan WuZhuo LiHuifen WangZhaoxia LiBo HuMinghui HeZhibo GaoXiaobing XuHongzan JiChaohui YuYi SunBaocai XingXiaobo YangHaiying ZhangAihua TanChunlei WuWeihua JiaShengping LiYi-Xin ZengHongbing ShenFuchu HeZengnan MoHongxing ZhangGangqiao ZhouNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016) |
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DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Yuanfeng Li Lanlan Si Yun Zhai Yanling Hu Zhibin Hu Jin-Xin Bei Bobo Xie Qian Ren Pengbo Cao Fei Yang Qingfeng Song Zhiyu Bao Haitao Zhang Yuqing Han Zhifu Wang Xi Chen Xia Xia Hongbo Yan Rui Wang Ying Zhang Chengming Gao Jinfeng Meng Xinyi Tu Xinqiang Liang Ying Cui Ying Liu Xiaopan Wu Zhuo Li Huifen Wang Zhaoxia Li Bo Hu Minghui He Zhibo Gao Xiaobing Xu Hongzan Ji Chaohui Yu Yi Sun Baocai Xing Xiaobo Yang Haiying Zhang Aihua Tan Chunlei Wu Weihua Jia Shengping Li Yi-Xin Zeng Hongbing Shen Fuchu He Zengnan Mo Hongxing Zhang Gangqiao Zhou Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese |
| description |
This genome-wide association study on persistent hepatitis B virus (HBV) infection among Chinese confirms previously associated genetic loci while discovering a novel protective locus at 8p21.3. The study also demonstrates the nearby gene INST10 suppresses HBV replication in vitro. |
| format |
article |
| author |
Yuanfeng Li Lanlan Si Yun Zhai Yanling Hu Zhibin Hu Jin-Xin Bei Bobo Xie Qian Ren Pengbo Cao Fei Yang Qingfeng Song Zhiyu Bao Haitao Zhang Yuqing Han Zhifu Wang Xi Chen Xia Xia Hongbo Yan Rui Wang Ying Zhang Chengming Gao Jinfeng Meng Xinyi Tu Xinqiang Liang Ying Cui Ying Liu Xiaopan Wu Zhuo Li Huifen Wang Zhaoxia Li Bo Hu Minghui He Zhibo Gao Xiaobing Xu Hongzan Ji Chaohui Yu Yi Sun Baocai Xing Xiaobo Yang Haiying Zhang Aihua Tan Chunlei Wu Weihua Jia Shengping Li Yi-Xin Zeng Hongbing Shen Fuchu He Zengnan Mo Hongxing Zhang Gangqiao Zhou |
| author_facet |
Yuanfeng Li Lanlan Si Yun Zhai Yanling Hu Zhibin Hu Jin-Xin Bei Bobo Xie Qian Ren Pengbo Cao Fei Yang Qingfeng Song Zhiyu Bao Haitao Zhang Yuqing Han Zhifu Wang Xi Chen Xia Xia Hongbo Yan Rui Wang Ying Zhang Chengming Gao Jinfeng Meng Xinyi Tu Xinqiang Liang Ying Cui Ying Liu Xiaopan Wu Zhuo Li Huifen Wang Zhaoxia Li Bo Hu Minghui He Zhibo Gao Xiaobing Xu Hongzan Ji Chaohui Yu Yi Sun Baocai Xing Xiaobo Yang Haiying Zhang Aihua Tan Chunlei Wu Weihua Jia Shengping Li Yi-Xin Zeng Hongbing Shen Fuchu He Zengnan Mo Hongxing Zhang Gangqiao Zhou |
| author_sort |
Yuanfeng Li |
| title |
Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese |
| title_short |
Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese |
| title_full |
Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese |
| title_fullStr |
Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese |
| title_full_unstemmed |
Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese |
| title_sort |
genome-wide association study identifies 8p21.3 associated with persistent hepatitis b virus infection among chinese |
| publisher |
Nature Portfolio |
| publishDate |
2016 |
| url |
https://doaj.org/article/c96b2ad71ac34492bddea1028cf80543 |
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