Spatiotemporal dynamics of single cell stiffness in the early developing ascidian chordate embryo

Fujii et al. investigate the stiffness of cells in ascidian embryos from the fertilised egg to the stage before gastrulation. They find two types of cell stiffening, occurring during cell division and in the interphase, the latter of which is associated with the Rho kinase pathway. They conclude tha...

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Autores principales: Yuki Fujii, Wataru C. Koizumi, Taichi Imai, Megumi Yokobori, Tomohiro Matsuo, Kotaro Oka, Kohji Hotta, Takaharu Okajima
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c9829359129740dc9439b2173216a084
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Sumario:Fujii et al. investigate the stiffness of cells in ascidian embryos from the fertilised egg to the stage before gastrulation. They find two types of cell stiffening, occurring during cell division and in the interphase, the latter of which is associated with the Rho kinase pathway. They conclude that the mechanical properties of early embryonic cells are regulated specifically at the single cell level.