Spatiotemporal dynamics of single cell stiffness in the early developing ascidian chordate embryo

Fujii et al. investigate the stiffness of cells in ascidian embryos from the fertilised egg to the stage before gastrulation. They find two types of cell stiffening, occurring during cell division and in the interphase, the latter of which is associated with the Rho kinase pathway. They conclude tha...

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Autores principales:	Yuki Fujii, Wataru C. Koizumi, Taichi Imai, Megumi Yokobori, Tomohiro Matsuo, Kotaro Oka, Kohji Hotta, Takaharu Okajima
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/c9829359129740dc9439b2173216a084
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spelling	oai:doaj.org-article:c9829359129740dc9439b2173216a0842021-12-02T16:30:46ZSpatiotemporal dynamics of single cell stiffness in the early developing ascidian chordate embryo10.1038/s42003-021-01869-w2399-3642https://doaj.org/article/c9829359129740dc9439b2173216a0842021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01869-whttps://doaj.org/toc/2399-3642Fujii et al. investigate the stiffness of cells in ascidian embryos from the fertilised egg to the stage before gastrulation. They find two types of cell stiffening, occurring during cell division and in the interphase, the latter of which is associated with the Rho kinase pathway. They conclude that the mechanical properties of early embryonic cells are regulated specifically at the single cell level.Yuki FujiiWataru C. KoizumiTaichi ImaiMegumi YokoboriTomohiro MatsuoKotaro OkaKohji HottaTakaharu OkajimaNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Yuki Fujii Wataru C. Koizumi Taichi Imai Megumi Yokobori Tomohiro Matsuo Kotaro Oka Kohji Hotta Takaharu Okajima Spatiotemporal dynamics of single cell stiffness in the early developing ascidian chordate embryo
description	Fujii et al. investigate the stiffness of cells in ascidian embryos from the fertilised egg to the stage before gastrulation. They find two types of cell stiffening, occurring during cell division and in the interphase, the latter of which is associated with the Rho kinase pathway. They conclude that the mechanical properties of early embryonic cells are regulated specifically at the single cell level.
format	article
author	Yuki Fujii Wataru C. Koizumi Taichi Imai Megumi Yokobori Tomohiro Matsuo Kotaro Oka Kohji Hotta Takaharu Okajima
author_facet	Yuki Fujii Wataru C. Koizumi Taichi Imai Megumi Yokobori Tomohiro Matsuo Kotaro Oka Kohji Hotta Takaharu Okajima
author_sort	Yuki Fujii
title	Spatiotemporal dynamics of single cell stiffness in the early developing ascidian chordate embryo
title_short	Spatiotemporal dynamics of single cell stiffness in the early developing ascidian chordate embryo
title_full	Spatiotemporal dynamics of single cell stiffness in the early developing ascidian chordate embryo
title_fullStr	Spatiotemporal dynamics of single cell stiffness in the early developing ascidian chordate embryo
title_full_unstemmed	Spatiotemporal dynamics of single cell stiffness in the early developing ascidian chordate embryo
title_sort	spatiotemporal dynamics of single cell stiffness in the early developing ascidian chordate embryo
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c9829359129740dc9439b2173216a084
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Spatiotemporal dynamics of single cell stiffness in the early developing ascidian chordate embryo

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