TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis

TREM-1 is a receptor that amplifies acute pro-inflammatory responses in infection. Here the authors show that TREM-1 plays an important role in atherosclerosis, a chronic and non-infectious disease, by critically skewing myelopoiesis towards preferential monocyte differentiation and by contributing...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Daniel Zysset, Benjamin Weber, Silvia Rihs, Jennifer Brasseit, Stefan Freigang, Carsten Riether, Yara Banz, Adelheid Cerwenka, Cedric Simillion, Pedro Marques-Vidal, Adrian F. Ochsenbein, Leslie Saurer, Christoph Mueller
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c98d1cb4aaf840bdbe679de4d5413ba5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c98d1cb4aaf840bdbe679de4d5413ba5
record_format	dspace
spelling	oai:doaj.org-article:c98d1cb4aaf840bdbe679de4d5413ba52021-12-02T16:50:15ZTREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis10.1038/ncomms131512041-1723https://doaj.org/article/c98d1cb4aaf840bdbe679de4d5413ba52016-10-01T00:00:00Zhttps://doi.org/10.1038/ncomms13151https://doaj.org/toc/2041-1723TREM-1 is a receptor that amplifies acute pro-inflammatory responses in infection. Here the authors show that TREM-1 plays an important role in atherosclerosis, a chronic and non-infectious disease, by critically skewing myelopoiesis towards preferential monocyte differentiation and by contributing to CD36-driven cellular lipid accumulation.Daniel ZyssetBenjamin WeberSilvia RihsJennifer BrasseitStefan FreigangCarsten RietherYara BanzAdelheid CerwenkaCedric SimillionPedro Marques-VidalAdrian F. OchsenbeinLeslie SaurerChristoph MuellerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Daniel Zysset Benjamin Weber Silvia Rihs Jennifer Brasseit Stefan Freigang Carsten Riether Yara Banz Adelheid Cerwenka Cedric Simillion Pedro Marques-Vidal Adrian F. Ochsenbein Leslie Saurer Christoph Mueller TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis
description	TREM-1 is a receptor that amplifies acute pro-inflammatory responses in infection. Here the authors show that TREM-1 plays an important role in atherosclerosis, a chronic and non-infectious disease, by critically skewing myelopoiesis towards preferential monocyte differentiation and by contributing to CD36-driven cellular lipid accumulation.
format	article
author	Daniel Zysset Benjamin Weber Silvia Rihs Jennifer Brasseit Stefan Freigang Carsten Riether Yara Banz Adelheid Cerwenka Cedric Simillion Pedro Marques-Vidal Adrian F. Ochsenbein Leslie Saurer Christoph Mueller
author_facet	Daniel Zysset Benjamin Weber Silvia Rihs Jennifer Brasseit Stefan Freigang Carsten Riether Yara Banz Adelheid Cerwenka Cedric Simillion Pedro Marques-Vidal Adrian F. Ochsenbein Leslie Saurer Christoph Mueller
author_sort	Daniel Zysset
title	TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis
title_short	TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis
title_full	TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis
title_fullStr	TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis
title_full_unstemmed	TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis
title_sort	trem-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/c98d1cb4aaf840bdbe679de4d5413ba5
work_keys_str_mv	AT danielzysset trem1linksdyslipidemiatoinflammationandlipiddepositioninatherosclerosis AT benjaminweber trem1linksdyslipidemiatoinflammationandlipiddepositioninatherosclerosis AT silviarihs trem1linksdyslipidemiatoinflammationandlipiddepositioninatherosclerosis AT jenniferbrasseit trem1linksdyslipidemiatoinflammationandlipiddepositioninatherosclerosis AT stefanfreigang trem1linksdyslipidemiatoinflammationandlipiddepositioninatherosclerosis AT carstenriether trem1linksdyslipidemiatoinflammationandlipiddepositioninatherosclerosis AT yarabanz trem1linksdyslipidemiatoinflammationandlipiddepositioninatherosclerosis AT adelheidcerwenka trem1linksdyslipidemiatoinflammationandlipiddepositioninatherosclerosis AT cedricsimillion trem1linksdyslipidemiatoinflammationandlipiddepositioninatherosclerosis AT pedromarquesvidal trem1linksdyslipidemiatoinflammationandlipiddepositioninatherosclerosis AT adrianfochsenbein trem1linksdyslipidemiatoinflammationandlipiddepositioninatherosclerosis AT lesliesaurer trem1linksdyslipidemiatoinflammationandlipiddepositioninatherosclerosis AT christophmueller trem1linksdyslipidemiatoinflammationandlipiddepositioninatherosclerosis
_version_	1718383066215350272

TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis

Ejemplares similares