Systemic control of immune cell development by integrated carbon dioxide and hypoxia chemosensation in Drosophila

In mammals, crosstalk between O2 and CO2 sensing central and peripheral chemoreceptors has been linked to functions of the hematopoietic system. Here, the authors show an evolutionarily relevant cascade involving multiple organs that links CO2- and O2-chemosensation to immune cell maturation in Dros...

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Autores principales: Bumsik Cho, Carrie M. Spratford, Sunggyu Yoon, Nuri Cha, Utpal Banerjee, Jiwon Shim
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c99106797d224954a4d11f17f8b5d09c
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Sumario:In mammals, crosstalk between O2 and CO2 sensing central and peripheral chemoreceptors has been linked to functions of the hematopoietic system. Here, the authors show an evolutionarily relevant cascade involving multiple organs that links CO2- and O2-chemosensation to immune cell maturation in Drosophila.