The effect of very low-calorie diets on renal and hepatic outcomes: a systematic review

Catherine Rolland,1 Alexandra Mavroeidi,2 Kelly L Johnston,3 John Broom1,31Centre for Obesity Research and Epidemiology (CORE), Faculty of Health and Social Care, Robert Gordon University, Aberdeen, Scotland, UK; 2School of Medical Sciences, College of Life Sciences and Medicine, University of Aberd...

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Autores principales:	Roll, C, Mavroeidi A, Johnston KL, Broom J
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/c99121638abf4aac904da24dfe460af5
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spelling	oai:doaj.org-article:c99121638abf4aac904da24dfe460af52021-12-02T02:10:14ZThe effect of very low-calorie diets on renal and hepatic outcomes: a systematic review1178-7007https://doaj.org/article/c99121638abf4aac904da24dfe460af52013-10-01T00:00:00Zhttp://www.dovepress.com/the-effect-of-very-low-calorie-diets-on-renal-and-hepatic-outcomes-a-s-a14660https://doaj.org/toc/1178-7007Catherine Rolland,1 Alexandra Mavroeidi,2 Kelly L Johnston,3 John Broom1,31Centre for Obesity Research and Epidemiology (CORE), Faculty of Health and Social Care, Robert Gordon University, Aberdeen, Scotland, UK; 2School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, Scotland, UK; 3LighterLife Ltd, Harlow, Essex, UKAbstract: Very low-calorie diets (VLCDs) are an effective means by which to induce clinically significant weight loss. However, their acceptance by health care practitioners and the public is generally lower than that for other nonsurgical weight loss methods. Whilst there is currently little evidence to suggest they have any detrimental effect on hepatic and renal health, data assessing these factors remain limited. We carried out a systematic review of the literature on randomized controlled trials that had a VLCD component and that reported outcomes for hepatic and renal health, published between January 1980 and December 2012. Cochrane criteria were followed, and eight out of 196 potential articles met the inclusion criteria. A total of 548 participants were recruited across the eight studies. All eight studies reported significant weight loss following the VLCD. Changes in hepatic and renal outcomes were variable but generally led to either no change or improvements in either of these. Due to the heterogeneity in the quality and methodology of the studies included, the effect of VLCDs on hepatic and renal outcomes remains unclear at this stage. Further standardized research is therefore required to fully assess the impact of VLCDs on these outcome measures, to better guide clinical practice.Keywords: obesity, liver, kidney, weight loss, healthRollCMavroeidi AJohnston KLBroom JDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2013, Iss default, Pp 393-401 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Roll C Mavroeidi A Johnston KL Broom J The effect of very low-calorie diets on renal and hepatic outcomes: a systematic review
description	Catherine Rolland,1 Alexandra Mavroeidi,2 Kelly L Johnston,3 John Broom1,31Centre for Obesity Research and Epidemiology (CORE), Faculty of Health and Social Care, Robert Gordon University, Aberdeen, Scotland, UK; 2School of Medical Sciences, College of Life Sciences and Medicine, University of Aberdeen, Aberdeen, Scotland, UK; 3LighterLife Ltd, Harlow, Essex, UKAbstract: Very low-calorie diets (VLCDs) are an effective means by which to induce clinically significant weight loss. However, their acceptance by health care practitioners and the public is generally lower than that for other nonsurgical weight loss methods. Whilst there is currently little evidence to suggest they have any detrimental effect on hepatic and renal health, data assessing these factors remain limited. We carried out a systematic review of the literature on randomized controlled trials that had a VLCD component and that reported outcomes for hepatic and renal health, published between January 1980 and December 2012. Cochrane criteria were followed, and eight out of 196 potential articles met the inclusion criteria. A total of 548 participants were recruited across the eight studies. All eight studies reported significant weight loss following the VLCD. Changes in hepatic and renal outcomes were variable but generally led to either no change or improvements in either of these. Due to the heterogeneity in the quality and methodology of the studies included, the effect of VLCDs on hepatic and renal outcomes remains unclear at this stage. Further standardized research is therefore required to fully assess the impact of VLCDs on these outcome measures, to better guide clinical practice.Keywords: obesity, liver, kidney, weight loss, health
format	article
author	Roll C Mavroeidi A Johnston KL Broom J
author_facet	Roll C Mavroeidi A Johnston KL Broom J
author_sort	Roll
title	The effect of very low-calorie diets on renal and hepatic outcomes: a systematic review
title_short	The effect of very low-calorie diets on renal and hepatic outcomes: a systematic review
title_full	The effect of very low-calorie diets on renal and hepatic outcomes: a systematic review
title_fullStr	The effect of very low-calorie diets on renal and hepatic outcomes: a systematic review
title_full_unstemmed	The effect of very low-calorie diets on renal and hepatic outcomes: a systematic review
title_sort	effect of very low-calorie diets on renal and hepatic outcomes: a systematic review
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/c99121638abf4aac904da24dfe460af5
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The effect of very low-calorie diets on renal and hepatic outcomes: a systematic review

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