Epidermal Growth Factor Receptor-PI3K Signaling Controls Cofilin Activity To Facilitate Herpes Simplex Virus 1 Entry into Neuronal Cells

ABSTRACT Herpes simplex virus type 1 (HSV-1) establishes latency in neurons and can cause severe disseminated infection with neurological impairment and high mortality. This neurodegeneration is thought to be tightly associated with virus-induced cytoskeleton disruption. Currently, the regulation pa...

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Autores principales: Kai Zheng, Yangfei Xiang, Xiao Wang, Qiaoli Wang, Meigong Zhong, Shaoxiang Wang, Xiaoyan Wang, Jianglin Fan, Kaio Kitazato, Yifei Wang
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://doaj.org/article/c99b8c533bb14195bf5367a36670724c
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