Status of 25-hydroxy vitamin D level in simple febrile seizures and its correlation with recurrence of seizures

Background: Febrile seizures are associated with a lot of modifiable and nonmodifiable risk factors. Extensive research is currently going on to discover more and more risk factors of febrile seizures, so that they can be modified to decrease their incidence and recurrence. Aims and Objectives: The...

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Autores principales:	Jehangir A Bhat, Tasleem Arif Bhat, Sajad A Sheikh, Zubair A Wani, Roshan Ara
Formato:	article
Lenguaje:	EN
Publicado:	Thieme Medical and Scientific Publishers Pvt. Ltd. 2020
Materias:	atypical febrile seizure correlation simple febrile seizures 25-hydroxy vitamin d Medicine R
Acceso en línea:	https://doaj.org/article/c9a512460d6d4077b5ed26367436b721
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spelling	oai:doaj.org-article:c9a512460d6d4077b5ed26367436b7212021-12-02T19:02:07ZStatus of 25-hydroxy vitamin D level in simple febrile seizures and its correlation with recurrence of seizures2231-07702249-446410.4103/ajm.ajm_57_19https://doaj.org/article/c9a512460d6d4077b5ed26367436b7212020-01-01T00:00:00Zhttp://www.thieme-connect.de/DOI/DOI?10.4103/ajm.ajm_57_19https://doaj.org/toc/2231-0770https://doaj.org/toc/2249-4464Background: Febrile seizures are associated with a lot of modifiable and nonmodifiable risk factors. Extensive research is currently going on to discover more and more risk factors of febrile seizures, so that they can be modified to decrease their incidence and recurrence. Aims and Objectives: The aim of this study was to determine the status of 25-hydroxy vitamin D in children presented with simple febrile seizures and to find its correlation with recurrence of seizures. Materials and Methods: This prospective observational study was conducted on 223 children of age group 7–59 months who presented with simple febrile seizures. 25-hydroxy vitamin D were sent to laboratory for quantitative estimation. All data were recorded, status of vitamin D in these children was analyzed, and statistical significance of correlation of vitamin D with the number of recurrent seizure episodes was derived. Statistical Analysis: The comparison among groups was carried out by analysis of variance and correlation was conducted by Pearson’s correlation analysis. A value of P < 0.05 was considered statistically significant. Results: 25-hydroxy vitamin D insufficiency was present in 43.5% of the children, deficiency in 30.85 %, and normal level in 25.56% of children who had simple febrile seizures. Majority of the children presented with recurrent episodes of seizures had vitamin D deficiency followed by insufficiency and normal level. Comparison of Vitamin D showed significant negative correlation (As vitamin D level increases frequency of seizure febrile seizure recurrence decreases and vice versa) with recurrence of simple febrile seizures. Conclusion: Deficiency of vitamin D is associated significantly with simple febrile seizures and their recurrence is negatively correlated with it.Jehangir A BhatTasleem Arif BhatSajad A SheikhZubair A WaniRoshan AraThieme Medical and Scientific Publishers Pvt. Ltd.articleatypical febrile seizurecorrelationsimple febrile seizures25-hydroxy vitamin dMedicineRENAvicenna Journal of Medicine, Vol 10, Iss 01, Pp 6-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	atypical febrile seizure correlation simple febrile seizures 25-hydroxy vitamin d Medicine R
spellingShingle	atypical febrile seizure correlation simple febrile seizures 25-hydroxy vitamin d Medicine R Jehangir A Bhat Tasleem Arif Bhat Sajad A Sheikh Zubair A Wani Roshan Ara Status of 25-hydroxy vitamin D level in simple febrile seizures and its correlation with recurrence of seizures
description	Background: Febrile seizures are associated with a lot of modifiable and nonmodifiable risk factors. Extensive research is currently going on to discover more and more risk factors of febrile seizures, so that they can be modified to decrease their incidence and recurrence. Aims and Objectives: The aim of this study was to determine the status of 25-hydroxy vitamin D in children presented with simple febrile seizures and to find its correlation with recurrence of seizures. Materials and Methods: This prospective observational study was conducted on 223 children of age group 7–59 months who presented with simple febrile seizures. 25-hydroxy vitamin D were sent to laboratory for quantitative estimation. All data were recorded, status of vitamin D in these children was analyzed, and statistical significance of correlation of vitamin D with the number of recurrent seizure episodes was derived. Statistical Analysis: The comparison among groups was carried out by analysis of variance and correlation was conducted by Pearson’s correlation analysis. A value of P < 0.05 was considered statistically significant. Results: 25-hydroxy vitamin D insufficiency was present in 43.5% of the children, deficiency in 30.85 %, and normal level in 25.56% of children who had simple febrile seizures. Majority of the children presented with recurrent episodes of seizures had vitamin D deficiency followed by insufficiency and normal level. Comparison of Vitamin D showed significant negative correlation (As vitamin D level increases frequency of seizure febrile seizure recurrence decreases and vice versa) with recurrence of simple febrile seizures. Conclusion: Deficiency of vitamin D is associated significantly with simple febrile seizures and their recurrence is negatively correlated with it.
format	article
author	Jehangir A Bhat Tasleem Arif Bhat Sajad A Sheikh Zubair A Wani Roshan Ara
author_facet	Jehangir A Bhat Tasleem Arif Bhat Sajad A Sheikh Zubair A Wani Roshan Ara
author_sort	Jehangir A Bhat
title	Status of 25-hydroxy vitamin D level in simple febrile seizures and its correlation with recurrence of seizures
title_short	Status of 25-hydroxy vitamin D level in simple febrile seizures and its correlation with recurrence of seizures
title_full	Status of 25-hydroxy vitamin D level in simple febrile seizures and its correlation with recurrence of seizures
title_fullStr	Status of 25-hydroxy vitamin D level in simple febrile seizures and its correlation with recurrence of seizures
title_full_unstemmed	Status of 25-hydroxy vitamin D level in simple febrile seizures and its correlation with recurrence of seizures
title_sort	status of 25-hydroxy vitamin d level in simple febrile seizures and its correlation with recurrence of seizures
publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
publishDate	2020
url	https://doaj.org/article/c9a512460d6d4077b5ed26367436b721
work_keys_str_mv	AT jehangirabhat statusof25hydroxyvitamindlevelinsimplefebrileseizuresanditscorrelationwithrecurrenceofseizures AT tasleemarifbhat statusof25hydroxyvitamindlevelinsimplefebrileseizuresanditscorrelationwithrecurrenceofseizures AT sajadasheikh statusof25hydroxyvitamindlevelinsimplefebrileseizuresanditscorrelationwithrecurrenceofseizures AT zubairawani statusof25hydroxyvitamindlevelinsimplefebrileseizuresanditscorrelationwithrecurrenceofseizures AT roshanara statusof25hydroxyvitamindlevelinsimplefebrileseizuresanditscorrelationwithrecurrenceofseizures
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Status of 25-hydroxy vitamin D level in simple febrile seizures and its correlation with recurrence of seizures

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