Mapping histone modifications in low cell number and single cells using antibody-guided chromatin tagmentation (ACT-seq)
The authors introduce ACT-seq: a Tn5-based method for rapidly profiling epigenetic marks in bulk-cell and single-cell samples. ACT-seq avoids many laborious or time-consuming steps required for similar techniques including chromatin fragmentation and end repair.
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Autores principales: | Benjamin Carter, Wai Lim Ku, Jee Youn Kang, Gangqing Hu, Jonathan Perrie, Qingsong Tang, Keji Zhao |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/c9a8a9af0a7e477299b738bebf2bf047 |
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