Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects

Obesity and the distribution of fat within the body are risk factors for cardiometabolic diseases. Here, Rask-Andersen et al. perform GWAS for bio-electrical impedance measurements in UK Biobank participants and identify 29 novel independent loci for fat distribution and a high degree of sex-heterog...

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Autores principales: Mathias Rask-Andersen, Torgny Karlsson, Weronica E. Ek, Åsa Johansson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/c9ab883c0ebe491abf1ad6a31f79d655
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Sumario:Obesity and the distribution of fat within the body are risk factors for cardiometabolic diseases. Here, Rask-Andersen et al. perform GWAS for bio-electrical impedance measurements in UK Biobank participants and identify 29 novel independent loci for fat distribution and a high degree of sex-heterogeneity.