Conformational plasticity and evolutionary analysis of the myotilin tandem Ig domains

Abstract Myotilin is a component of the sarcomere where it plays an important role in organisation and maintenance of Z-disk integrity. This involves direct binding to F-actin and filamin C, a function mediated by its Ig domain pair. While the structures of these two individual domains are known, in...

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Autores principales: Vid Puž, Miha Pavšič, Brigita Lenarčič, Kristina Djinović-Carugo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c9ab95b6f7574c8ab9cb2d8daa190733
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