Gammaherpesvirus Usurps Host IL-17 Signaling To Support the Establishment of Chronic Infection

Gammaherpesviruses establish lifelong infections in a majority of humans and are associated with B cell lymphomas. IL-17A is a host cytokine that plays a well-established role in the clearance of bacterial and fungal infections; however, the role of IL-17A in viral infections is poorly understood.

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Autores principales: C. N. Jondle, K. E. Johnson, C. Aurubin, P. Sylvester, G. Xin, W. Cui, A. R. Huppler, V. L. Tarakanova
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/c9ad0ea93967482ba9c34a7d837170bc
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Sumario:Gammaherpesviruses establish lifelong infections in a majority of humans and are associated with B cell lymphomas. IL-17A is a host cytokine that plays a well-established role in the clearance of bacterial and fungal infections; however, the role of IL-17A in viral infections is poorly understood.