Development of a model of medication review for use in clinical practice: Bristol medication review model

Abstract Background Medication review is a core aspect of medicine optimisation, yet existing models of review vary substantially in structure and content and are not necessarily easy to implement in clinical practice. This study aimed to use evidence from the existing literature to identify key med...

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Autores principales:	D. McCahon, R. E. Denholm, A. L. Huntley, S. Dawson, P. Duncan, R. A. Payne
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Medicine optimisation Prescribing Medication review Medicine R
Acceso en línea:	https://doaj.org/article/c9afebba94294c27a3c84a0a3f94550c
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spelling	oai:doaj.org-article:c9afebba94294c27a3c84a0a3f94550c2021-11-14T12:17:02ZDevelopment of a model of medication review for use in clinical practice: Bristol medication review model10.1186/s12916-021-02136-91741-7015https://doaj.org/article/c9afebba94294c27a3c84a0a3f94550c2021-11-01T00:00:00Zhttps://doi.org/10.1186/s12916-021-02136-9https://doaj.org/toc/1741-7015Abstract Background Medication review is a core aspect of medicine optimisation, yet existing models of review vary substantially in structure and content and are not necessarily easy to implement in clinical practice. This study aimed to use evidence from the existing literature to identify key medication review components and use this to inform the design of an improved review model. Methods A systematic review was conducted (PROSPERO: CRD42018109788) to identify randomised control trials of stand-alone medication review in adults (18+ years). The review updated that by Huiskes et al. (BMC Fam Pract. 18:5, 2017), using the same search strategy implemented in MEDLINE and Embase. Studies were assessed using the Cochrane risk of bias tool. Key review components were identified, alongside relevant clinical and health service outcomes. A working group (patients, doctors and pharmacists) developed the model through an iterative consensus process (appraisal of documents plus group discussions), working from the systematic review findings, brief evidence summaries for core review components and examples of previous models, to agree on the main purpose of the review model, overarching model structure, review components and supporting material. Results We identified 28 unique studies, with moderate bias overall. Consistent medication review components included reconciliation (26 studies), safety assessment (22), suboptimal treatment (19), patient knowledge/preferences (18), adherence (14), over-the-counter therapy (13) and drug monitoring (10). There was limited evidence from studies for improvement in key clinical outcomes. The review structure was underpinned by patient values and preferences, with parallel information gathering and evaluation stages, feeding into the final decision-making and implementation. Most key components identified in the literature were included. The final model was considered to benefit from a patient-centred, holistic approach, which captured both patient-orientated and medication-focused problems, and aligned with traditional consultation methods thus facilitating implementation in practice. Conclusions The Bristol Medication Review Model provides a framework for standardised delivery of structured reviews. The model has the potential for use by all healthcare professionals with relevant clinical experience and is designed to offer flexibility of implementation not limited to a particular healthcare setting.D. McCahonR. E. DenholmA. L. HuntleyS. DawsonP. DuncanR. A. PayneBMCarticleMedicine optimisationPrescribingMedication reviewMedicineRENBMC Medicine, Vol 19, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine optimisation Prescribing Medication review Medicine R
spellingShingle	Medicine optimisation Prescribing Medication review Medicine R D. McCahon R. E. Denholm A. L. Huntley S. Dawson P. Duncan R. A. Payne Development of a model of medication review for use in clinical practice: Bristol medication review model
description	Abstract Background Medication review is a core aspect of medicine optimisation, yet existing models of review vary substantially in structure and content and are not necessarily easy to implement in clinical practice. This study aimed to use evidence from the existing literature to identify key medication review components and use this to inform the design of an improved review model. Methods A systematic review was conducted (PROSPERO: CRD42018109788) to identify randomised control trials of stand-alone medication review in adults (18+ years). The review updated that by Huiskes et al. (BMC Fam Pract. 18:5, 2017), using the same search strategy implemented in MEDLINE and Embase. Studies were assessed using the Cochrane risk of bias tool. Key review components were identified, alongside relevant clinical and health service outcomes. A working group (patients, doctors and pharmacists) developed the model through an iterative consensus process (appraisal of documents plus group discussions), working from the systematic review findings, brief evidence summaries for core review components and examples of previous models, to agree on the main purpose of the review model, overarching model structure, review components and supporting material. Results We identified 28 unique studies, with moderate bias overall. Consistent medication review components included reconciliation (26 studies), safety assessment (22), suboptimal treatment (19), patient knowledge/preferences (18), adherence (14), over-the-counter therapy (13) and drug monitoring (10). There was limited evidence from studies for improvement in key clinical outcomes. The review structure was underpinned by patient values and preferences, with parallel information gathering and evaluation stages, feeding into the final decision-making and implementation. Most key components identified in the literature were included. The final model was considered to benefit from a patient-centred, holistic approach, which captured both patient-orientated and medication-focused problems, and aligned with traditional consultation methods thus facilitating implementation in practice. Conclusions The Bristol Medication Review Model provides a framework for standardised delivery of structured reviews. The model has the potential for use by all healthcare professionals with relevant clinical experience and is designed to offer flexibility of implementation not limited to a particular healthcare setting.
format	article
author	D. McCahon R. E. Denholm A. L. Huntley S. Dawson P. Duncan R. A. Payne
author_facet	D. McCahon R. E. Denholm A. L. Huntley S. Dawson P. Duncan R. A. Payne
author_sort	D. McCahon
title	Development of a model of medication review for use in clinical practice: Bristol medication review model
title_short	Development of a model of medication review for use in clinical practice: Bristol medication review model
title_full	Development of a model of medication review for use in clinical practice: Bristol medication review model
title_fullStr	Development of a model of medication review for use in clinical practice: Bristol medication review model
title_full_unstemmed	Development of a model of medication review for use in clinical practice: Bristol medication review model
title_sort	development of a model of medication review for use in clinical practice: bristol medication review model
publisher	BMC
publishDate	2021
url	https://doaj.org/article/c9afebba94294c27a3c84a0a3f94550c
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Development of a model of medication review for use in clinical practice: Bristol medication review model

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