Rule-based cell systems model of aging using feedback loop motifs mediated by stress responses.
Investigating the complex systems dynamics of the aging process requires integration of a broad range of cellular processes describing damage and functional decline co-existing with adaptive and protective regulatory mechanisms. We evolve an integrated generic cell network to represent the connectiv...
Guardado en:
Autores principales: | Andres Kriete, William J Bosl, Glenn Booker |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2010
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Materias: | |
Acceso en línea: | https://doaj.org/article/c9b0d1145bcc48f8a85cd12cb540420b |
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