Rule-based cell systems model of aging using feedback loop motifs mediated by stress responses.
Investigating the complex systems dynamics of the aging process requires integration of a broad range of cellular processes describing damage and functional decline co-existing with adaptive and protective regulatory mechanisms. We evolve an integrated generic cell network to represent the connectiv...
Enregistré dans:
Auteurs principaux: | Andres Kriete, William J Bosl, Glenn Booker |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2010
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/c9b0d1145bcc48f8a85cd12cb540420b |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Feedback Loops and Facilitation: Catalyzing Transformational Multi-Stakeholder Refugee Response Partnerships
par: Jaime Moreno-Serna, et autres
Publié: (2021) -
An autoregulatory negative feedback loop controls thermomorphogenesis in Arabidopsis.
par: Sanghwa Lee, et autres
Publié: (2021) -
The register shift rules for βαβ-motifs for de novo protein design.
par: Hiroto Murata, et autres
Publié: (2021) -
A positive feedback loop mediated by Sigma X enhances expression of the streptococcal regulator ComR
par: Rabia Khan, et autres
Publié: (2017) -
A PXR-mediated negative feedback loop attenuates the expression of CYP3A in response to the PXR agonist pregnenalone-16α-carbonitrile.
par: Ian Bailey, et autres
Publié: (2011)