ATRX promotes heterochromatin formation to protect cells from G-quadruplex DNA-mediated stress
ATRX is a chromatin remodeling protein, which loss has been associated to replication stress, DNA damage, and DNA repair failures that drive genome instability. Here the authors reveal that ATRX protects genomic integrity at G4-containing regions by maintaining these regions in a closed heterochroma...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/c9b46c0c43fd49e8b61774788526fb9b |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|