Deaminase-independent inhibition of parvoviruses by the APOBEC3A cytidine deaminase.
The APOBEC3 proteins form a multigene family of cytidine deaminases with inhibitory activity against viruses and retrotransposons. In contrast to APOBEC3G (A3G), APOBEC3A (A3A) has no effect on lentiviruses but dramatically inhibits replication of the parvovirus adeno-associated virus (AAV). To stud...
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Auteurs principaux: | Iñigo Narvaiza, Daniel C Linfesty, Benjamin N Greener, Yoshiyuki Hakata, David J Pintel, Eric Logue, Nathaniel R Landau, Matthew D Weitzman |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2009
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Accès en ligne: | https://doaj.org/article/c9be6e30441e4dc4b3b23d56c804e04b |
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