A PPARγ-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesis
Abstract Activation of the endothelium by pro-inflammatory stimuli plays a key role in the pathogenesis of a multitude of vascular diseases. Angiogenesis is a crucial component of the vascular response associated with inflammatory signaling. The CD40/CD40 ligand dyad in endothelial cells (EC) has a...
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Autores principales: | Aram Lee, Irinna Papangeli, Youngsook Park, Ha-neul Jeong, Jihea Choi, Hyesoo Kang, Ha-neul Jo, Jongmin Kim, Hyung J. Chun |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/c9d724390ac74109ab3a7959e35b8668 |
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