A PPARγ-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesis

Abstract Activation of the endothelium by pro-inflammatory stimuli plays a key role in the pathogenesis of a multitude of vascular diseases. Angiogenesis is a crucial component of the vascular response associated with inflammatory signaling. The CD40/CD40 ligand dyad in endothelial cells (EC) has a...

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Autores principales: Aram Lee, Irinna Papangeli, Youngsook Park, Ha-neul Jeong, Jihea Choi, Hyesoo Kang, Ha-neul Jo, Jongmin Kim, Hyung J. Chun
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c9d724390ac74109ab3a7959e35b8668
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