High‐efficiency delivery of CRISPR‐Cas9 by engineered probiotics enables precise microbiome editing

Abstract Antibiotic resistance threatens our ability to treat infectious diseases, spurring interest in alternative antimicrobial technologies. The use of bacterial conjugation to deliver CRISPR‐cas systems programmed to precisely eliminate antibiotic‐resistant bacteria represents a promising approa...

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Autores principales: Kevin Neil, Nancy Allard, Patricia Roy, Frédéric Grenier, Alfredo Menendez, Vincent Burrus, Sébastien Rodrigue
Formato: article
Lenguaje:EN
Publicado: Wiley 2021
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Acceso en línea:https://doaj.org/article/c9ddf6574182493ea5f2edf2a1f7117a
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