Inference of RNA decay rate from transcriptional profiling highlights the regulatory programs of Alzheimer’s disease
“mRNA abundance is determined by the rates of transcription and decay. Here, the authors propose a method for estimating the rate of differential mRNA decay from RNA-seq data and model mRNA stability in the brain, suggesting a link between mRNA stability and Alzheimer’s disease.”
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Autores principales: | Rached Alkallas, Lisa Fish, Hani Goodarzi, Hamed S. Najafabadi |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/c9decdf8979e4cb5bcf04691b5455dd8 |
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