Proximity proteomics identifies PAK4 as a component of Afadin–Nectin junctions
PAK4 is a kinase involved in cell-cell junctions, though the identify of the local protein network involving PAK4 is unclear. Here, the authors performed proximity proteomic analysis on mammalian PAK4 and find that PAK4 is associated with Afadin-dependent junctions, and report putative PAK4 phosph...
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| Autores principales: | , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/c9e161aeee0b4d8fb9c114a3126f6415 |
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| Sumario: | PAK4 is a kinase involved in cell-cell junctions, though the identify of the local protein network involving PAK4 is unclear. Here, the authors performed proximity proteomic analysis on mammalian PAK4 and find that PAK4 is associated with Afadin-dependent junctions, and report putative PAK4 phosphorylation substrates at this site. |
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