Separation and purification of plant terpenoids from biotransformation

Abstract The production of plant terpenoids through biotransformation has undoubtedly become one of the research hotspots, and the continuous upgrading of the corresponding downstream technology is also particularly important. Downstream technology is the indispensable technical channel for the indu...

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Autores principales:	Linhao Chen, Yaru Pang, Yan Luo, Xu Cheng, Bo Lv, Chun Li
Formato:	article
Lenguaje:	EN
Publicado:	Wiley-VCH 2021
Materias:	intelligent microbial cell factories plant terpenoids purification separation synthetic biology Biotechnology TP248.13-248.65
Acceso en línea:	https://doaj.org/article/c9f1c0191d4c433182ba74fcf25af78e
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spelling	oai:doaj.org-article:c9f1c0191d4c433182ba74fcf25af78e2021-11-09T05:07:05ZSeparation and purification of plant terpenoids from biotransformation1618-28631618-024010.1002/elsc.202100014https://doaj.org/article/c9f1c0191d4c433182ba74fcf25af78e2021-11-01T00:00:00Zhttps://doi.org/10.1002/elsc.202100014https://doaj.org/toc/1618-0240https://doaj.org/toc/1618-2863Abstract The production of plant terpenoids through biotransformation has undoubtedly become one of the research hotspots, and the continuous upgrading of the corresponding downstream technology is also particularly important. Downstream technology is the indispensable technical channel for the industrialization of plant terpenoids. How to efficiently separate high‐purity products from complex microbial fermentation broths or enzyme‐catalyzed reactions to achieve high separation rates, high returns and environmental friendliness has become the focus of research in recent years. This review mainly introduces the common separation methods of plant terpenoids based on biotransformation from the perspectives of engineering strain construction, unit separation technology, product properties and added value. Then, further attention was paid to the application prospects of intelligent cell factories and control in the separation of plant terpenoids. Finally, some current challenges and prospects are proposed, which provide possible directions and guidance for the separation and purification of terpenoids and even industrialization.Linhao ChenYaru PangYan LuoXu ChengBo LvChun LiWiley-VCHarticleintelligent microbial cell factoriesplant terpenoidspurificationseparationsynthetic biologyBiotechnologyTP248.13-248.65ENEngineering in Life Sciences, Vol 21, Iss 11, Pp 724-738 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	intelligent microbial cell factories plant terpenoids purification separation synthetic biology Biotechnology TP248.13-248.65
spellingShingle	intelligent microbial cell factories plant terpenoids purification separation synthetic biology Biotechnology TP248.13-248.65 Linhao Chen Yaru Pang Yan Luo Xu Cheng Bo Lv Chun Li Separation and purification of plant terpenoids from biotransformation
description	Abstract The production of plant terpenoids through biotransformation has undoubtedly become one of the research hotspots, and the continuous upgrading of the corresponding downstream technology is also particularly important. Downstream technology is the indispensable technical channel for the industrialization of plant terpenoids. How to efficiently separate high‐purity products from complex microbial fermentation broths or enzyme‐catalyzed reactions to achieve high separation rates, high returns and environmental friendliness has become the focus of research in recent years. This review mainly introduces the common separation methods of plant terpenoids based on biotransformation from the perspectives of engineering strain construction, unit separation technology, product properties and added value. Then, further attention was paid to the application prospects of intelligent cell factories and control in the separation of plant terpenoids. Finally, some current challenges and prospects are proposed, which provide possible directions and guidance for the separation and purification of terpenoids and even industrialization.
format	article
author	Linhao Chen Yaru Pang Yan Luo Xu Cheng Bo Lv Chun Li
author_facet	Linhao Chen Yaru Pang Yan Luo Xu Cheng Bo Lv Chun Li
author_sort	Linhao Chen
title	Separation and purification of plant terpenoids from biotransformation
title_short	Separation and purification of plant terpenoids from biotransformation
title_full	Separation and purification of plant terpenoids from biotransformation
title_fullStr	Separation and purification of plant terpenoids from biotransformation
title_full_unstemmed	Separation and purification of plant terpenoids from biotransformation
title_sort	separation and purification of plant terpenoids from biotransformation
publisher	Wiley-VCH
publishDate	2021
url	https://doaj.org/article/c9f1c0191d4c433182ba74fcf25af78e
work_keys_str_mv	AT linhaochen separationandpurificationofplantterpenoidsfrombiotransformation AT yarupang separationandpurificationofplantterpenoidsfrombiotransformation AT yanluo separationandpurificationofplantterpenoidsfrombiotransformation AT xucheng separationandpurificationofplantterpenoidsfrombiotransformation AT bolv separationandpurificationofplantterpenoidsfrombiotransformation AT chunli separationandpurificationofplantterpenoidsfrombiotransformation
_version_	1718441332205158400

Separation and purification of plant terpenoids from biotransformation

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