Severe acute respiratory syndrome coronavirus 2 vaccines: The good, the bad, and the ugly

The coronavirus disease pandemic is caused by the highly infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The infection can result in mild-to-severe disease, although many asymptomatic infections are described. There are many types of vaccines with different characteristics,...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Katia N. Estrada-Medrano, Alejandro Rodríguez-Garza, Mario C. Salinas-Carmona, David Gómez-Almaguer
Formato:	article
Lenguaje:	EN ES
Publicado:	Permanyer 2021
Materias:	Coronavirus disease. Vaccines. Vaccine development. Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/c9f49ef7696d4eb290ccf6dfc1061e49
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:c9f49ef7696d4eb290ccf6dfc1061e49
record_format	dspace
spelling	oai:doaj.org-article:c9f49ef7696d4eb290ccf6dfc1061e492021-11-04T09:25:05ZSevere acute respiratory syndrome coronavirus 2 vaccines: The good, the bad, and the ugly10.24875/RMU.M210000571665-57962530-0709https://doaj.org/article/c9f49ef7696d4eb290ccf6dfc1061e492021-04-01T00:00:00Zhttps://www.medicinauniversitaria.org/frame_esp.php?id=133https://doaj.org/toc/1665-5796https://doaj.org/toc/2530-0709The coronavirus disease pandemic is caused by the highly infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The infection can result in mild-to-severe disease, although many asymptomatic infections are described. There are many types of vaccines with different characteristics, and many have reached Phase III of clinical trials. In this review, we included the main vaccines approved worldwide, including those approved in Mexico. Vaccine-induced immune thrombotic thrombocytopenia has been described, especially in adenovirus vector vaccines. There are specific concerns around vaccine safety and efficacy in special populations such as pregnant women and immunosuppressed individuals. Even though the evidence is scarce, vaccine application remains recommended in most cases. We concluded that the risks of adverse effects from the vaccines are minimal compared to the current risk of contracting the SARS-COV-2 infection. The benefit of applying the vaccines is greater than not applying them at all. Katia N. Estrada-MedranoAlejandro Rodríguez-GarzaMario C. Salinas-CarmonaDavid Gómez-AlmaguerPermanyerarticleCoronavirus disease. Vaccines. Vaccine development.Medicine (General)R5-920ENESMedicina Universitaria, Vol 23, Iss 2 (2021)
institution	DOAJ
collection	DOAJ
language	EN ES
topic	Coronavirus disease. Vaccines. Vaccine development. Medicine (General) R5-920
spellingShingle	Coronavirus disease. Vaccines. Vaccine development. Medicine (General) R5-920 Katia N. Estrada-Medrano Alejandro Rodríguez-Garza Mario C. Salinas-Carmona David Gómez-Almaguer Severe acute respiratory syndrome coronavirus 2 vaccines: The good, the bad, and the ugly
description	The coronavirus disease pandemic is caused by the highly infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The infection can result in mild-to-severe disease, although many asymptomatic infections are described. There are many types of vaccines with different characteristics, and many have reached Phase III of clinical trials. In this review, we included the main vaccines approved worldwide, including those approved in Mexico. Vaccine-induced immune thrombotic thrombocytopenia has been described, especially in adenovirus vector vaccines. There are specific concerns around vaccine safety and efficacy in special populations such as pregnant women and immunosuppressed individuals. Even though the evidence is scarce, vaccine application remains recommended in most cases. We concluded that the risks of adverse effects from the vaccines are minimal compared to the current risk of contracting the SARS-COV-2 infection. The benefit of applying the vaccines is greater than not applying them at all.
format	article
author	Katia N. Estrada-Medrano Alejandro Rodríguez-Garza Mario C. Salinas-Carmona David Gómez-Almaguer
author_facet	Katia N. Estrada-Medrano Alejandro Rodríguez-Garza Mario C. Salinas-Carmona David Gómez-Almaguer
author_sort	Katia N. Estrada-Medrano
title	Severe acute respiratory syndrome coronavirus 2 vaccines: The good, the bad, and the ugly
title_short	Severe acute respiratory syndrome coronavirus 2 vaccines: The good, the bad, and the ugly
title_full	Severe acute respiratory syndrome coronavirus 2 vaccines: The good, the bad, and the ugly
title_fullStr	Severe acute respiratory syndrome coronavirus 2 vaccines: The good, the bad, and the ugly
title_full_unstemmed	Severe acute respiratory syndrome coronavirus 2 vaccines: The good, the bad, and the ugly
title_sort	severe acute respiratory syndrome coronavirus 2 vaccines: the good, the bad, and the ugly
publisher	Permanyer
publishDate	2021
url	https://doaj.org/article/c9f49ef7696d4eb290ccf6dfc1061e49
work_keys_str_mv	AT katianestradamedrano severeacuterespiratorysyndromecoronavirus2vaccinesthegoodthebadandtheugly AT alejandrorodriguezgarza severeacuterespiratorysyndromecoronavirus2vaccinesthegoodthebadandtheugly AT mariocsalinascarmona severeacuterespiratorysyndromecoronavirus2vaccinesthegoodthebadandtheugly AT davidgomezalmaguer severeacuterespiratorysyndromecoronavirus2vaccinesthegoodthebadandtheugly
_version_	1718444991698698240

Severe acute respiratory syndrome coronavirus 2 vaccines: The good, the bad, and the ugly

Ejemplares similares