Evaluation of LDL goal achievement in statin consumption, south east of Iran

Abstract Lipid goal achievement and statin consumption were estimated at extreme/very-high/high/moderate and low cardiovascular risk categories. In the cross-sectional study, 585 patients treated with statin therapy referring to the heart clinic of Birjand were recruited. Patients were classified an...

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Autores principales:	Malihe Aghasizadeh, Saeede Khosravi Bizhaem, Mahin Baniasadi, Mohammad Reza Khazdair, Toba Kazemi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/c9f79b4f9b4a4215aba9060c68a2b8e4
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spelling	oai:doaj.org-article:c9f79b4f9b4a4215aba9060c68a2b8e42021-12-02T15:00:55ZEvaluation of LDL goal achievement in statin consumption, south east of Iran10.1038/s41598-021-90228-02045-2322https://doaj.org/article/c9f79b4f9b4a4215aba9060c68a2b8e42021-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-90228-0https://doaj.org/toc/2045-2322Abstract Lipid goal achievement and statin consumption were estimated at extreme/very-high/high/moderate and low cardiovascular risk categories. In the cross-sectional study, 585 patients treated with statin therapy referring to the heart clinic of Birjand were recruited. Patients were classified and examined LDL-C values and the proportion reaching targets according to the American Association of Clinical Endocrinologists guideline. Three patterns of statin use (high/moderate/low-intensity statin therapy) in all patients were examined and attainments of LDL-C goal in cardiovascular risk groups have been demonstrated. Over half the populations (57.6%) were in the very-high CVD risk group. The results showed that the proportion of patients meeting total LDL-C goal values according to the guidelines was 43.4%. The frequency of patient had achievement LDL goal lower in high-intensity pattern (N = 13, 2.3%), compared with moderate (N = 496, 86.1%) and low-intensity patterns (N = 67, 11.6%). In general, LDL-C goal achievement was greatest with moderate-intensity statin use. LDL-C reduction after statin consumption was estimated about one-third of the studied population. It seems likely that the achievement of a therapeutic target for serum lipids such as LDL-C improved is far more cost-effective and would be able to reach the target LDL as well changing the type and intensity of statins.Malihe AghasizadehSaeede Khosravi BizhaemMahin BaniasadiMohammad Reza KhazdairToba KazemiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Malihe Aghasizadeh Saeede Khosravi Bizhaem Mahin Baniasadi Mohammad Reza Khazdair Toba Kazemi Evaluation of LDL goal achievement in statin consumption, south east of Iran
description	Abstract Lipid goal achievement and statin consumption were estimated at extreme/very-high/high/moderate and low cardiovascular risk categories. In the cross-sectional study, 585 patients treated with statin therapy referring to the heart clinic of Birjand were recruited. Patients were classified and examined LDL-C values and the proportion reaching targets according to the American Association of Clinical Endocrinologists guideline. Three patterns of statin use (high/moderate/low-intensity statin therapy) in all patients were examined and attainments of LDL-C goal in cardiovascular risk groups have been demonstrated. Over half the populations (57.6%) were in the very-high CVD risk group. The results showed that the proportion of patients meeting total LDL-C goal values according to the guidelines was 43.4%. The frequency of patient had achievement LDL goal lower in high-intensity pattern (N = 13, 2.3%), compared with moderate (N = 496, 86.1%) and low-intensity patterns (N = 67, 11.6%). In general, LDL-C goal achievement was greatest with moderate-intensity statin use. LDL-C reduction after statin consumption was estimated about one-third of the studied population. It seems likely that the achievement of a therapeutic target for serum lipids such as LDL-C improved is far more cost-effective and would be able to reach the target LDL as well changing the type and intensity of statins.
format	article
author	Malihe Aghasizadeh Saeede Khosravi Bizhaem Mahin Baniasadi Mohammad Reza Khazdair Toba Kazemi
author_facet	Malihe Aghasizadeh Saeede Khosravi Bizhaem Mahin Baniasadi Mohammad Reza Khazdair Toba Kazemi
author_sort	Malihe Aghasizadeh
title	Evaluation of LDL goal achievement in statin consumption, south east of Iran
title_short	Evaluation of LDL goal achievement in statin consumption, south east of Iran
title_full	Evaluation of LDL goal achievement in statin consumption, south east of Iran
title_fullStr	Evaluation of LDL goal achievement in statin consumption, south east of Iran
title_full_unstemmed	Evaluation of LDL goal achievement in statin consumption, south east of Iran
title_sort	evaluation of ldl goal achievement in statin consumption, south east of iran
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/c9f79b4f9b4a4215aba9060c68a2b8e4
work_keys_str_mv	AT maliheaghasizadeh evaluationofldlgoalachievementinstatinconsumptionsoutheastofiran AT saeedekhosravibizhaem evaluationofldlgoalachievementinstatinconsumptionsoutheastofiran AT mahinbaniasadi evaluationofldlgoalachievementinstatinconsumptionsoutheastofiran AT mohammadrezakhazdair evaluationofldlgoalachievementinstatinconsumptionsoutheastofiran AT tobakazemi evaluationofldlgoalachievementinstatinconsumptionsoutheastofiran
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Evaluation of LDL goal achievement in statin consumption, south east of Iran

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