DNA methylation repels targeting of Arabidopsis REF6

REF6 is a H3K27me3 histone demethylase that targets regions of active chromatin in the Arabidopsis genome. Here Qiu et al. show that REF6 preferentially binds unmethylated DNA via its zinc-finger domains suggesting that DNA methylation might deter REF6 binding in heterochromatin.

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Autores principales:	Qi Qiu, Hailiang Mei, Xian Deng, Kaixuan He, Baixing Wu, Qingqing Yao, Jixiang Zhang, Falong Lu, Jinbiao Ma, Xiaofeng Cao
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/c9fddf88484c4306b766b9bf3ea12f9a
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:c9fddf88484c4306b766b9bf3ea12f9a2021-12-02T17:02:19ZDNA methylation repels targeting of Arabidopsis REF610.1038/s41467-019-10026-12041-1723https://doaj.org/article/c9fddf88484c4306b766b9bf3ea12f9a2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10026-1https://doaj.org/toc/2041-1723REF6 is a H3K27me3 histone demethylase that targets regions of active chromatin in the Arabidopsis genome. Here Qiu et al. show that REF6 preferentially binds unmethylated DNA via its zinc-finger domains suggesting that DNA methylation might deter REF6 binding in heterochromatin.Qi QiuHailiang MeiXian DengKaixuan HeBaixing WuQingqing YaoJixiang ZhangFalong LuJinbiao MaXiaofeng CaoNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Qi Qiu Hailiang Mei Xian Deng Kaixuan He Baixing Wu Qingqing Yao Jixiang Zhang Falong Lu Jinbiao Ma Xiaofeng Cao DNA methylation repels targeting of Arabidopsis REF6
description	REF6 is a H3K27me3 histone demethylase that targets regions of active chromatin in the Arabidopsis genome. Here Qiu et al. show that REF6 preferentially binds unmethylated DNA via its zinc-finger domains suggesting that DNA methylation might deter REF6 binding in heterochromatin.
format	article
author	Qi Qiu Hailiang Mei Xian Deng Kaixuan He Baixing Wu Qingqing Yao Jixiang Zhang Falong Lu Jinbiao Ma Xiaofeng Cao
author_facet	Qi Qiu Hailiang Mei Xian Deng Kaixuan He Baixing Wu Qingqing Yao Jixiang Zhang Falong Lu Jinbiao Ma Xiaofeng Cao
author_sort	Qi Qiu
title	DNA methylation repels targeting of Arabidopsis REF6
title_short	DNA methylation repels targeting of Arabidopsis REF6
title_full	DNA methylation repels targeting of Arabidopsis REF6
title_fullStr	DNA methylation repels targeting of Arabidopsis REF6
title_full_unstemmed	DNA methylation repels targeting of Arabidopsis REF6
title_sort	dna methylation repels targeting of arabidopsis ref6
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/c9fddf88484c4306b766b9bf3ea12f9a
work_keys_str_mv	AT qiqiu dnamethylationrepelstargetingofarabidopsisref6 AT hailiangmei dnamethylationrepelstargetingofarabidopsisref6 AT xiandeng dnamethylationrepelstargetingofarabidopsisref6 AT kaixuanhe dnamethylationrepelstargetingofarabidopsisref6 AT baixingwu dnamethylationrepelstargetingofarabidopsisref6 AT qingqingyao dnamethylationrepelstargetingofarabidopsisref6 AT jixiangzhang dnamethylationrepelstargetingofarabidopsisref6 AT falonglu dnamethylationrepelstargetingofarabidopsisref6 AT jinbiaoma dnamethylationrepelstargetingofarabidopsisref6 AT xiaofengcao dnamethylationrepelstargetingofarabidopsisref6
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DNA methylation repels targeting of Arabidopsis REF6

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