Plasmodium DNA-mediated TLR9 activation of T-bet+ B cells contributes to autoimmune anaemia during malaria
Autoimmune anaemia often accompanies Plasmodium infection and malaria, but how anaemia is induced is still unclear. Here the authors show that Plasmodium DNA, together with interferon-γ, can activate B cells to induce auto-antibodies that recognize red blood cells and promote their removal to contri...
Guardado en:
Autores principales: | J. Rivera-Correa, J. J. Guthmiller, R. Vijay, C. Fernandez-Arias, M. A. Pardo-Ruge, S. Gonzalez, N. S. Butler, A. Rodriguez |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/ca046ba7684d4a96b9538349ba8e7523 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Prunella vulgaris L. Attenuates Experimental Autoimmune Thyroiditis by Inhibiting HMGB1/TLR9 Signaling
por: Guo Q, et al.
Publicado: (2021) -
SIDEROBLASTIC ANAEMIA–A HITHERTO UNRCCGNIZED CAUSE OF UNEXPLAINED ANAEMIA
por: Kamran Nazir Ahmad, et al.
Publicado: (2018) -
Duration of protection against malaria and anaemia provided by intermittent preventive treatment in infants in Navrongo, Ghana.
por: Matthew Cairns, et al.
Publicado: (2008) -
Predictors of outcome in childhood Plasmodium falciparum malaria
por: Harsita Patel, et al.
Publicado: (2020) -
Endothelial glycocalyx degradation and disease severity in Plasmodium vivax and Plasmodium knowlesi malaria
por: Bridget E. Barber, et al.
Publicado: (2021)