Vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder

Nilfer Sahin,1 Hatice Altun,2 Ergül Belge Kurutas,3 Damla Balkan1 1Department of Child and Adolescent Psychiatry, Muğla Sıtkı Koçman University, Muğla, Turkey; 2Department of Child and Adolescent Psychiatry, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey; 3Department...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sahin N, Altun H, Kurutas EB, Balkan D
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2018
Materias:	attention deficit hyperactivity disorder vitamin D vitamin D receptor Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/ca15cbb6687f4de68e7baaec95bc6cba
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ca15cbb6687f4de68e7baaec95bc6cba
record_format	dspace
spelling	oai:doaj.org-article:ca15cbb6687f4de68e7baaec95bc6cba2021-12-02T02:55:04ZVitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder1178-2021https://doaj.org/article/ca15cbb6687f4de68e7baaec95bc6cba2018-02-01T00:00:00Zhttps://www.dovepress.com/vitamin-d-and-vitamin-d-receptor-levels-in-children-with-attention-def-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Nilfer Sahin,1 Hatice Altun,2 Ergül Belge Kurutas,3 Damla Balkan1 1Department of Child and Adolescent Psychiatry, Muğla Sıtkı Koçman University, Muğla, Turkey; 2Department of Child and Adolescent Psychiatry, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey; 3Department of Biochemistry, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey Objective: In this study, we aimed to evaluate vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder (ADHD). Patients and methods: In this cross-sectional study, a total of 80 children including 40 ADHD patients (aged 6–12 years; 28 males and 12 females) and 40 age-, sex-, and season of blood collection-matched controls (aged 6–12 years; 25 males and 15 females) were enrolled. Serum vitamin D and vitamin D receptor levels and calcium, phosphorus, and alkaline phosphatase were measured. The vitamin D receptor levels in the serum were measured using the quantitative sandwich enzyme immunoassay technique. Results: Serum vitamin D and vitamin D receptor levels were found to be significantly lower in children with ADHD compared to healthy controls. No significant differences were found in serum calcium, phosphorus, and alkaline phosphatase levels. No significant differences were found among the ADHD subtypes in terms of serum vitamin D, vitamin D receptor, calcium, phosphorus and alkaline phosphatase levels. Conclusion: This study suggests that children with ADHD have lower levels of vitamin D and vitamin D receptor. According to the authors’ knowledge, this is the first study to describe vitamin D receptor levels in ADHD. Keywords: attention-deficit/hyperactivity disorder, vitamin D, vitamin D receptorSahin NAltun HKurutas EBBalkan DDove Medical Pressarticleattention deficit hyperactivity disordervitamin Dvitamin D receptorNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 14, Pp 581-585 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	attention deficit hyperactivity disorder vitamin D vitamin D receptor Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	attention deficit hyperactivity disorder vitamin D vitamin D receptor Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Sahin N Altun H Kurutas EB Balkan D Vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder
description	Nilfer Sahin,1 Hatice Altun,2 Ergül Belge Kurutas,3 Damla Balkan1 1Department of Child and Adolescent Psychiatry, Muğla Sıtkı Koçman University, Muğla, Turkey; 2Department of Child and Adolescent Psychiatry, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey; 3Department of Biochemistry, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey Objective: In this study, we aimed to evaluate vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder (ADHD). Patients and methods: In this cross-sectional study, a total of 80 children including 40 ADHD patients (aged 6–12 years; 28 males and 12 females) and 40 age-, sex-, and season of blood collection-matched controls (aged 6–12 years; 25 males and 15 females) were enrolled. Serum vitamin D and vitamin D receptor levels and calcium, phosphorus, and alkaline phosphatase were measured. The vitamin D receptor levels in the serum were measured using the quantitative sandwich enzyme immunoassay technique. Results: Serum vitamin D and vitamin D receptor levels were found to be significantly lower in children with ADHD compared to healthy controls. No significant differences were found in serum calcium, phosphorus, and alkaline phosphatase levels. No significant differences were found among the ADHD subtypes in terms of serum vitamin D, vitamin D receptor, calcium, phosphorus and alkaline phosphatase levels. Conclusion: This study suggests that children with ADHD have lower levels of vitamin D and vitamin D receptor. According to the authors’ knowledge, this is the first study to describe vitamin D receptor levels in ADHD. Keywords: attention-deficit/hyperactivity disorder, vitamin D, vitamin D receptor
format	article
author	Sahin N Altun H Kurutas EB Balkan D
author_facet	Sahin N Altun H Kurutas EB Balkan D
author_sort	Sahin N
title	Vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder
title_short	Vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder
title_full	Vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder
title_fullStr	Vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder
title_full_unstemmed	Vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder
title_sort	vitamin d and vitamin d receptor levels in children with attention-deficit/hyperactivity disorder
publisher	Dove Medical Press
publishDate	2018
url	https://doaj.org/article/ca15cbb6687f4de68e7baaec95bc6cba
work_keys_str_mv	AT sahinn vitamindandvitamindreceptorlevelsinchildrenwithattentiondeficithyperactivitydisorder AT altunh vitamindandvitamindreceptorlevelsinchildrenwithattentiondeficithyperactivitydisorder AT kurutaseb vitamindandvitamindreceptorlevelsinchildrenwithattentiondeficithyperactivitydisorder AT balkand vitamindandvitamindreceptorlevelsinchildrenwithattentiondeficithyperactivitydisorder
_version_	1718402068870332416

Vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder

Ejemplares similares