INFLUENCE OF ANTIBODIES AGAINST CTLA-4 AND PD-1 UPON QUANTITIES OF THEIR TARGET RECEPTORS
Inhibitory receptors CTLA-4 and PD-1 (immune checkpoints) play a key role in regulation of immune reactions. They suppress excessive immune response against pathogenic microbes and prevent autoimmune reactions. The immune checkpoints are targets of the modern effective therapy based on human and hum...
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | RU |
| Publié: |
SPb RAACI
2019
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| Accès en ligne: | https://doaj.org/article/ca1be543ea6845e3bdecf5e1eee5a835 |
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