Massive computational acceleration by using neural networks to emulate mechanism-based biological models

Mechanistic models provide valuable insights, but large-scale simulations are computationally expensive. Here, the authors show that it is possible to explore the dynamics of a mechanistic model over a large set of parameters by training an artificial neural network on a smaller set of simulations.

Guardado en:

Detalles Bibliográficos
Autores principales:	Shangying Wang, Kai Fan, Nan Luo, Yangxiaolu Cao, Feilun Wu, Carolyn Zhang, Katherine A. Heller, Lingchong You
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ca202084bd924cf29c6afd7e9e5166b7
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ca202084bd924cf29c6afd7e9e5166b7
record_format	dspace
spelling	oai:doaj.org-article:ca202084bd924cf29c6afd7e9e5166b72021-12-02T15:35:55ZMassive computational acceleration by using neural networks to emulate mechanism-based biological models10.1038/s41467-019-12342-y2041-1723https://doaj.org/article/ca202084bd924cf29c6afd7e9e5166b72019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12342-yhttps://doaj.org/toc/2041-1723Mechanistic models provide valuable insights, but large-scale simulations are computationally expensive. Here, the authors show that it is possible to explore the dynamics of a mechanistic model over a large set of parameters by training an artificial neural network on a smaller set of simulations.Shangying WangKai FanNan LuoYangxiaolu CaoFeilun WuCarolyn ZhangKatherine A. HellerLingchong YouNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shangying Wang Kai Fan Nan Luo Yangxiaolu Cao Feilun Wu Carolyn Zhang Katherine A. Heller Lingchong You Massive computational acceleration by using neural networks to emulate mechanism-based biological models
description	Mechanistic models provide valuable insights, but large-scale simulations are computationally expensive. Here, the authors show that it is possible to explore the dynamics of a mechanistic model over a large set of parameters by training an artificial neural network on a smaller set of simulations.
format	article
author	Shangying Wang Kai Fan Nan Luo Yangxiaolu Cao Feilun Wu Carolyn Zhang Katherine A. Heller Lingchong You
author_facet	Shangying Wang Kai Fan Nan Luo Yangxiaolu Cao Feilun Wu Carolyn Zhang Katherine A. Heller Lingchong You
author_sort	Shangying Wang
title	Massive computational acceleration by using neural networks to emulate mechanism-based biological models
title_short	Massive computational acceleration by using neural networks to emulate mechanism-based biological models
title_full	Massive computational acceleration by using neural networks to emulate mechanism-based biological models
title_fullStr	Massive computational acceleration by using neural networks to emulate mechanism-based biological models
title_full_unstemmed	Massive computational acceleration by using neural networks to emulate mechanism-based biological models
title_sort	massive computational acceleration by using neural networks to emulate mechanism-based biological models
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ca202084bd924cf29c6afd7e9e5166b7
work_keys_str_mv	AT shangyingwang massivecomputationalaccelerationbyusingneuralnetworkstoemulatemechanismbasedbiologicalmodels AT kaifan massivecomputationalaccelerationbyusingneuralnetworkstoemulatemechanismbasedbiologicalmodels AT nanluo massivecomputationalaccelerationbyusingneuralnetworkstoemulatemechanismbasedbiologicalmodels AT yangxiaolucao massivecomputationalaccelerationbyusingneuralnetworkstoemulatemechanismbasedbiologicalmodels AT feilunwu massivecomputationalaccelerationbyusingneuralnetworkstoemulatemechanismbasedbiologicalmodels AT carolynzhang massivecomputationalaccelerationbyusingneuralnetworkstoemulatemechanismbasedbiologicalmodels AT katherineaheller massivecomputationalaccelerationbyusingneuralnetworkstoemulatemechanismbasedbiologicalmodels AT lingchongyou massivecomputationalaccelerationbyusingneuralnetworkstoemulatemechanismbasedbiologicalmodels
_version_	1718386439645822976

Massive computational acceleration by using neural networks to emulate mechanism-based biological models

Ejemplares similares