Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome

In eukaryotes, ribosome biogenesis culminates in the cytoplasm with the maturation of the peptidyl transfer center (PTC). Here the authors describe several structures of intermediates in late nuclear and cytoplasmic maturation of the large ribosomal subunit that reveal the tightly-choreographed sequ...

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Autores principales:	Yi Zhou, Sharmishtha Musalgaonkar, Arlen W. Johnson, David W. Taylor
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ca23fa7fbae046ac84ff66d7fbc30108
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spelling	oai:doaj.org-article:ca23fa7fbae046ac84ff66d7fbc301082021-12-02T14:38:37ZTightly-orchestrated rearrangements govern catalytic center assembly of the ribosome10.1038/s41467-019-08880-02041-1723https://doaj.org/article/ca23fa7fbae046ac84ff66d7fbc301082019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08880-0https://doaj.org/toc/2041-1723In eukaryotes, ribosome biogenesis culminates in the cytoplasm with the maturation of the peptidyl transfer center (PTC). Here the authors describe several structures of intermediates in late nuclear and cytoplasmic maturation of the large ribosomal subunit that reveal the tightly-choreographed sequence of protein and RNA rearrangements that lead to the completion of the PTC.Yi ZhouSharmishtha MusalgaonkarArlen W. JohnsonDavid W. TaylorNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yi Zhou Sharmishtha Musalgaonkar Arlen W. Johnson David W. Taylor Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome
description	In eukaryotes, ribosome biogenesis culminates in the cytoplasm with the maturation of the peptidyl transfer center (PTC). Here the authors describe several structures of intermediates in late nuclear and cytoplasmic maturation of the large ribosomal subunit that reveal the tightly-choreographed sequence of protein and RNA rearrangements that lead to the completion of the PTC.
format	article
author	Yi Zhou Sharmishtha Musalgaonkar Arlen W. Johnson David W. Taylor
author_facet	Yi Zhou Sharmishtha Musalgaonkar Arlen W. Johnson David W. Taylor
author_sort	Yi Zhou
title	Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome
title_short	Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome
title_full	Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome
title_fullStr	Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome
title_full_unstemmed	Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome
title_sort	tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ca23fa7fbae046ac84ff66d7fbc30108
work_keys_str_mv	AT yizhou tightlyorchestratedrearrangementsgoverncatalyticcenterassemblyoftheribosome AT sharmishthamusalgaonkar tightlyorchestratedrearrangementsgoverncatalyticcenterassemblyoftheribosome AT arlenwjohnson tightlyorchestratedrearrangementsgoverncatalyticcenterassemblyoftheribosome AT davidwtaylor tightlyorchestratedrearrangementsgoverncatalyticcenterassemblyoftheribosome
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Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome

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