Quantitative interactome of a membrane Bcl-2 network identifies a hierarchy of complexes for apoptosis regulation
The permeabilization of the mitochondrial outer membrane to induce apoptosis is regulated by complex interactions between Bcl-2 family members. Here the authors develop a quantitative interactome of a membrane Bcl-2 network and identify a hierarchy of protein complexes in apoptosis induction.
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Autores principales: | Stephanie Bleicken, Annika Hantusch, Kushal Kumar Das, Tancred Frickey, Ana J. Garcia-Saez |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/ca24f04c17a149e2b6bbdd1ada2b7e7d |
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