Quantitative interactome of a membrane Bcl-2 network identifies a hierarchy of complexes for apoptosis regulation

The permeabilization of the mitochondrial outer membrane to induce apoptosis is regulated by complex interactions between Bcl-2 family members. Here the authors develop a quantitative interactome of a membrane Bcl-2 network and identify a hierarchy of protein complexes in apoptosis induction.

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Auteurs principaux: Stephanie Bleicken, Annika Hantusch, Kushal Kumar Das, Tancred Frickey, Ana J. Garcia-Saez
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Q
Accès en ligne:https://doaj.org/article/ca24f04c17a149e2b6bbdd1ada2b7e7d
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