Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation

How cardiomyocytes mature and what regulates this is unclear. Here, the authors use single-cell analysis to examine how the population of murine cardiac fibroblasts changes during development and affects maturation of cardiomyocytes.

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Detalles Bibliográficos
Autores principales: Yin Wang, Fang Yao, Lipeng Wang, Zheng Li, Zongna Ren, Dandan Li, Mingzhi Zhang, Leng Han, Shi-qiang Wang, Bingying Zhou, Li Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ca40843e733c4c80982a106f3235506e
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Sumario:How cardiomyocytes mature and what regulates this is unclear. Here, the authors use single-cell analysis to examine how the population of murine cardiac fibroblasts changes during development and affects maturation of cardiomyocytes.