Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment

Features of major depressive disorder including lack of motivation, sleep disruption and cognitive deficit have been modelled in rodents. Here, the authors develop a new method to elicit a depression-like state inDrosophila, and uncover separable roles for different serotonin receptors in depression...

Full description

Saved in:
Bibliographic Details
Main Authors: Ariane-Saskia Ries, Tim Hermanns, Burkhard Poeck, Roland Strauss
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Q
Online Access:https://doaj.org/article/ca4249022afd4ce2abf1cea0c9c7a7d7
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Features of major depressive disorder including lack of motivation, sleep disruption and cognitive deficit have been modelled in rodents. Here, the authors develop a new method to elicit a depression-like state inDrosophila, and uncover separable roles for different serotonin receptors in depression-like behaviour.