Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment
Features of major depressive disorder including lack of motivation, sleep disruption and cognitive deficit have been modelled in rodents. Here, the authors develop a new method to elicit a depression-like state inDrosophila, and uncover separable roles for different serotonin receptors in depression...
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Nature Portfolio
2017
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oai:doaj.org-article:ca4249022afd4ce2abf1cea0c9c7a7d72021-12-02T15:39:06ZSerotonin modulates a depression-like state in Drosophila responsive to lithium treatment10.1038/ncomms157382041-1723https://doaj.org/article/ca4249022afd4ce2abf1cea0c9c7a7d72017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15738https://doaj.org/toc/2041-1723Features of major depressive disorder including lack of motivation, sleep disruption and cognitive deficit have been modelled in rodents. Here, the authors develop a new method to elicit a depression-like state inDrosophila, and uncover separable roles for different serotonin receptors in depression-like behaviour.Ariane-Saskia RiesTim HermannsBurkhard PoeckRoland StraussNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
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Science Q Ariane-Saskia Ries Tim Hermanns Burkhard Poeck Roland Strauss Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment |
description |
Features of major depressive disorder including lack of motivation, sleep disruption and cognitive deficit have been modelled in rodents. Here, the authors develop a new method to elicit a depression-like state inDrosophila, and uncover separable roles for different serotonin receptors in depression-like behaviour. |
format |
article |
author |
Ariane-Saskia Ries Tim Hermanns Burkhard Poeck Roland Strauss |
author_facet |
Ariane-Saskia Ries Tim Hermanns Burkhard Poeck Roland Strauss |
author_sort |
Ariane-Saskia Ries |
title |
Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment |
title_short |
Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment |
title_full |
Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment |
title_fullStr |
Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment |
title_full_unstemmed |
Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment |
title_sort |
serotonin modulates a depression-like state in drosophila responsive to lithium treatment |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/ca4249022afd4ce2abf1cea0c9c7a7d7 |
work_keys_str_mv |
AT arianesaskiaries serotoninmodulatesadepressionlikestateindrosophilaresponsivetolithiumtreatment AT timhermanns serotoninmodulatesadepressionlikestateindrosophilaresponsivetolithiumtreatment AT burkhardpoeck serotoninmodulatesadepressionlikestateindrosophilaresponsivetolithiumtreatment AT rolandstrauss serotoninmodulatesadepressionlikestateindrosophilaresponsivetolithiumtreatment |
_version_ |
1718386015616368640 |