Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment

Features of major depressive disorder including lack of motivation, sleep disruption and cognitive deficit have been modelled in rodents. Here, the authors develop a new method to elicit a depression-like state inDrosophila, and uncover separable roles for different serotonin receptors in depression...

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Auteurs principaux:	Ariane-Saskia Ries, Tim Hermanns, Burkhard Poeck, Roland Strauss
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2017
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/ca4249022afd4ce2abf1cea0c9c7a7d7
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spelling	oai:doaj.org-article:ca4249022afd4ce2abf1cea0c9c7a7d72021-12-02T15:39:06ZSerotonin modulates a depression-like state in Drosophila responsive to lithium treatment10.1038/ncomms157382041-1723https://doaj.org/article/ca4249022afd4ce2abf1cea0c9c7a7d72017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15738https://doaj.org/toc/2041-1723Features of major depressive disorder including lack of motivation, sleep disruption and cognitive deficit have been modelled in rodents. Here, the authors develop a new method to elicit a depression-like state inDrosophila, and uncover separable roles for different serotonin receptors in depression-like behaviour.Ariane-Saskia RiesTim HermannsBurkhard PoeckRoland StraussNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ariane-Saskia Ries Tim Hermanns Burkhard Poeck Roland Strauss Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment
description	Features of major depressive disorder including lack of motivation, sleep disruption and cognitive deficit have been modelled in rodents. Here, the authors develop a new method to elicit a depression-like state inDrosophila, and uncover separable roles for different serotonin receptors in depression-like behaviour.
format	article
author	Ariane-Saskia Ries Tim Hermanns Burkhard Poeck Roland Strauss
author_facet	Ariane-Saskia Ries Tim Hermanns Burkhard Poeck Roland Strauss
author_sort	Ariane-Saskia Ries
title	Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment
title_short	Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment
title_full	Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment
title_fullStr	Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment
title_full_unstemmed	Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment
title_sort	serotonin modulates a depression-like state in drosophila responsive to lithium treatment
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/ca4249022afd4ce2abf1cea0c9c7a7d7
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_version_	1718386015616368640

Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment

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