Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment

Features of major depressive disorder including lack of motivation, sleep disruption and cognitive deficit have been modelled in rodents. Here, the authors develop a new method to elicit a depression-like state inDrosophila, and uncover separable roles for different serotonin receptors in depression...

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Autores principales: Ariane-Saskia Ries, Tim Hermanns, Burkhard Poeck, Roland Strauss
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/ca4249022afd4ce2abf1cea0c9c7a7d7
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spelling oai:doaj.org-article:ca4249022afd4ce2abf1cea0c9c7a7d72021-12-02T15:39:06ZSerotonin modulates a depression-like state in Drosophila responsive to lithium treatment10.1038/ncomms157382041-1723https://doaj.org/article/ca4249022afd4ce2abf1cea0c9c7a7d72017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15738https://doaj.org/toc/2041-1723Features of major depressive disorder including lack of motivation, sleep disruption and cognitive deficit have been modelled in rodents. Here, the authors develop a new method to elicit a depression-like state inDrosophila, and uncover separable roles for different serotonin receptors in depression-like behaviour.Ariane-Saskia RiesTim HermannsBurkhard PoeckRoland StraussNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ariane-Saskia Ries
Tim Hermanns
Burkhard Poeck
Roland Strauss
Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment
description Features of major depressive disorder including lack of motivation, sleep disruption and cognitive deficit have been modelled in rodents. Here, the authors develop a new method to elicit a depression-like state inDrosophila, and uncover separable roles for different serotonin receptors in depression-like behaviour.
format article
author Ariane-Saskia Ries
Tim Hermanns
Burkhard Poeck
Roland Strauss
author_facet Ariane-Saskia Ries
Tim Hermanns
Burkhard Poeck
Roland Strauss
author_sort Ariane-Saskia Ries
title Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment
title_short Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment
title_full Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment
title_fullStr Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment
title_full_unstemmed Serotonin modulates a depression-like state in Drosophila responsive to lithium treatment
title_sort serotonin modulates a depression-like state in drosophila responsive to lithium treatment
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/ca4249022afd4ce2abf1cea0c9c7a7d7
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