Allergic Diseases: A Comprehensive Review on Risk Factors, Immunological Mechanisms, Link with COVID-19, Potential Treatments, and Role of Allergen Bioinformatics

The prevalence of allergic diseases is regarded as one of the key challenges in health worldwide. Although the precise mechanisms underlying this rapid increase in prevalence are unknown, emerging evidence suggests that genetic and environmental factors play a significant role. The immune system, mi...

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Autor principal: Fahad M. Aldakheel
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Lenguaje:EN
Publicado: MDPI AG 2021
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Acceso en línea:https://doaj.org/article/ca42a9495f1d4bf2949d55f109d8b69b
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spelling oai:doaj.org-article:ca42a9495f1d4bf2949d55f109d8b69b2021-11-25T17:51:10ZAllergic Diseases: A Comprehensive Review on Risk Factors, Immunological Mechanisms, Link with COVID-19, Potential Treatments, and Role of Allergen Bioinformatics10.3390/ijerph1822121051660-46011661-7827https://doaj.org/article/ca42a9495f1d4bf2949d55f109d8b69b2021-11-01T00:00:00Zhttps://www.mdpi.com/1660-4601/18/22/12105https://doaj.org/toc/1661-7827https://doaj.org/toc/1660-4601The prevalence of allergic diseases is regarded as one of the key challenges in health worldwide. Although the precise mechanisms underlying this rapid increase in prevalence are unknown, emerging evidence suggests that genetic and environmental factors play a significant role. The immune system, microbiota, viruses, and bacteria have all been linked to the onset of allergy disorders in recent years. Avoiding allergen exposure is the best treatment option; however, steroids, antihistamines, and other symptom-relieving drugs are also used. Allergen bioinformatics encompasses both computational tools/methods and allergen-related data resources for managing, archiving, and analyzing allergological data. This study highlights allergy-promoting mechanisms, algorithms, and concepts in allergen bioinformatics, as well as major areas for future research in the field of allergology.Fahad M. AldakheelMDPI AGarticleallergyimmune systemmicrobiotaallergologyallergen bioinformaticsMedicineRENInternational Journal of Environmental Research and Public Health, Vol 18, Iss 12105, p 12105 (2021)
institution DOAJ
collection DOAJ
language EN
topic allergy
immune system
microbiota
allergology
allergen bioinformatics
Medicine
R
spellingShingle allergy
immune system
microbiota
allergology
allergen bioinformatics
Medicine
R
Fahad M. Aldakheel
Allergic Diseases: A Comprehensive Review on Risk Factors, Immunological Mechanisms, Link with COVID-19, Potential Treatments, and Role of Allergen Bioinformatics
description The prevalence of allergic diseases is regarded as one of the key challenges in health worldwide. Although the precise mechanisms underlying this rapid increase in prevalence are unknown, emerging evidence suggests that genetic and environmental factors play a significant role. The immune system, microbiota, viruses, and bacteria have all been linked to the onset of allergy disorders in recent years. Avoiding allergen exposure is the best treatment option; however, steroids, antihistamines, and other symptom-relieving drugs are also used. Allergen bioinformatics encompasses both computational tools/methods and allergen-related data resources for managing, archiving, and analyzing allergological data. This study highlights allergy-promoting mechanisms, algorithms, and concepts in allergen bioinformatics, as well as major areas for future research in the field of allergology.
format article
author Fahad M. Aldakheel
author_facet Fahad M. Aldakheel
author_sort Fahad M. Aldakheel
title Allergic Diseases: A Comprehensive Review on Risk Factors, Immunological Mechanisms, Link with COVID-19, Potential Treatments, and Role of Allergen Bioinformatics
title_short Allergic Diseases: A Comprehensive Review on Risk Factors, Immunological Mechanisms, Link with COVID-19, Potential Treatments, and Role of Allergen Bioinformatics
title_full Allergic Diseases: A Comprehensive Review on Risk Factors, Immunological Mechanisms, Link with COVID-19, Potential Treatments, and Role of Allergen Bioinformatics
title_fullStr Allergic Diseases: A Comprehensive Review on Risk Factors, Immunological Mechanisms, Link with COVID-19, Potential Treatments, and Role of Allergen Bioinformatics
title_full_unstemmed Allergic Diseases: A Comprehensive Review on Risk Factors, Immunological Mechanisms, Link with COVID-19, Potential Treatments, and Role of Allergen Bioinformatics
title_sort allergic diseases: a comprehensive review on risk factors, immunological mechanisms, link with covid-19, potential treatments, and role of allergen bioinformatics
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/ca42a9495f1d4bf2949d55f109d8b69b
work_keys_str_mv AT fahadmaldakheel allergicdiseasesacomprehensivereviewonriskfactorsimmunologicalmechanismslinkwithcovid19potentialtreatmentsandroleofallergenbioinformatics
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