Four cases of intraepithelial neoplasia of vulva: Case report

Background and Objective: VIN (Vulval Intraepithelial Neoplasia) is a rare disease that can be observed in young females. In this study, four VIN cases referred to the gynecologic oncology clinic of Ghaem and Omid hospitals (Mashhad) during a year are going to be introduced. Cases: Four patients (Me...

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Autores principales: Z Yousefi, F Homaei, N Sharifi, S Kadkhodayan
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Lenguaje:EN
FA
Publicado: Babol University of Medical Sciences 2004
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spelling oai:doaj.org-article:ca444adeb1be4a3ab0cf77f05e080d032021-11-10T09:16:12ZFour cases of intraepithelial neoplasia of vulva: Case report1561-41072251-7170https://doaj.org/article/ca444adeb1be4a3ab0cf77f05e080d032004-07-01T00:00:00Zhttp://jbums.org/article-1-2703-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: VIN (Vulval Intraepithelial Neoplasia) is a rare disease that can be observed in young females. In this study, four VIN cases referred to the gynecologic oncology clinic of Ghaem and Omid hospitals (Mashhad) during a year are going to be introduced. Cases: Four patients (Mean age 30 years) suffering from mass and itching vulva referred to our center. All had multifocal lesions. Risk factors such as HIV, STD and smoking showed negative results. Despite not having the possibility of examining HPV infection, two patients had koilocytosis pattern in pathologic examination. No patients had CIN and other related genital cancers. Surgery treatment in the form of local excision during the usage of acetic acid was performed in the operating ward. In two patients, the removed marginal tissue showed positive malignancy results had gone through orthovoltage radiotherapy. The recurrence was observed in one patient after one year who was reoperated in the form of skinning vulvectomy. Conclusion: According to this fact that the major cause of VIN is STD and in more than 80% of patients is HPV infection the decrease in incidence of STD can especially lead to VIN decrease and vulva cancer naturally.Z YousefiF HomaeiN SharifiS KadkhodayanBabol University of Medical Sciencesarticlehuman papilloma viruscarcinoma of the vulvaintraepithelial neoplasia of the vulvaMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 6, Iss 3, Pp 59-63 (2004)
institution DOAJ
collection DOAJ
language EN
FA
topic human papilloma virus
carcinoma of the vulva
intraepithelial neoplasia of the vulva
Medicine
R
Medicine (General)
R5-920
spellingShingle human papilloma virus
carcinoma of the vulva
intraepithelial neoplasia of the vulva
Medicine
R
Medicine (General)
R5-920
Z Yousefi
F Homaei
N Sharifi
S Kadkhodayan
Four cases of intraepithelial neoplasia of vulva: Case report
description Background and Objective: VIN (Vulval Intraepithelial Neoplasia) is a rare disease that can be observed in young females. In this study, four VIN cases referred to the gynecologic oncology clinic of Ghaem and Omid hospitals (Mashhad) during a year are going to be introduced. Cases: Four patients (Mean age 30 years) suffering from mass and itching vulva referred to our center. All had multifocal lesions. Risk factors such as HIV, STD and smoking showed negative results. Despite not having the possibility of examining HPV infection, two patients had koilocytosis pattern in pathologic examination. No patients had CIN and other related genital cancers. Surgery treatment in the form of local excision during the usage of acetic acid was performed in the operating ward. In two patients, the removed marginal tissue showed positive malignancy results had gone through orthovoltage radiotherapy. The recurrence was observed in one patient after one year who was reoperated in the form of skinning vulvectomy. Conclusion: According to this fact that the major cause of VIN is STD and in more than 80% of patients is HPV infection the decrease in incidence of STD can especially lead to VIN decrease and vulva cancer naturally.
format article
author Z Yousefi
F Homaei
N Sharifi
S Kadkhodayan
author_facet Z Yousefi
F Homaei
N Sharifi
S Kadkhodayan
author_sort Z Yousefi
title Four cases of intraepithelial neoplasia of vulva: Case report
title_short Four cases of intraepithelial neoplasia of vulva: Case report
title_full Four cases of intraepithelial neoplasia of vulva: Case report
title_fullStr Four cases of intraepithelial neoplasia of vulva: Case report
title_full_unstemmed Four cases of intraepithelial neoplasia of vulva: Case report
title_sort four cases of intraepithelial neoplasia of vulva: case report
publisher Babol University of Medical Sciences
publishDate 2004
url https://doaj.org/article/ca444adeb1be4a3ab0cf77f05e080d03
work_keys_str_mv AT zyousefi fourcasesofintraepithelialneoplasiaofvulvacasereport
AT fhomaei fourcasesofintraepithelialneoplasiaofvulvacasereport
AT nsharifi fourcasesofintraepithelialneoplasiaofvulvacasereport
AT skadkhodayan fourcasesofintraepithelialneoplasiaofvulvacasereport
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